Applied Technology for Neuro-Psychology Lab. - ATN-P Lab., Istituto Auxologico Italiano, Milan, Italy.
Med Hypotheses. 2012 Feb;78(2):254-7. doi: 10.1016/j.mehy.2011.10.039. Epub 2011 Nov 17.
Evidence from psychology and neuroscience indicates that our spatial experience, including the bodily one, involves the integration of different sensory inputs within two different reference frames egocentric (body as reference of first-person experience) and allocentric (body as object in the physical world). Even if functional relations between these two frames are usually limited, they influence each other during the interaction between long- and short-term memory processes in spatial cognition. If, for some reasons, this process is impaired, the egocentric sensory inputs are no more able to update the contents of the allocentric representation of the body: the subject is locked to it. In the presented perspective, subjects with eating disorders are locked to an allocentric representation of their body, stored in long-term memory (allocentric lock). A significant role in the locking may be played by the medial temporal lobe, and in particular by the connection between the hippocampal complex and amygdala. The differences between exogenous and endogenous causes of the lock may also explain the difference between bulimia nervosa and anorexia nervosa.
心理学和神经科学的证据表明，我们的空间体验，包括身体体验，涉及到不同感觉输入在两个不同参照系中的整合：以自我为中心（身体作为第一人称经验的参照系）和以物体为中心（身体作为物理世界中的物体）。即使这两个框架之间的功能关系通常是有限的，但在空间认知中长时记忆和短时记忆过程的相互作用中，它们会相互影响。如果由于某些原因，这个过程受到损害，以自我为中心的感觉输入就不再能够更新身体的以物体为中心的表示的内容：主体就被锁定在其中。在本文所提出的观点中，饮食失调的患者被锁定在他们的身体的以物体为中心的表示中，存储在长时记忆中（以物体为中心的锁定）。在锁定过程中，内侧颞叶，特别是海马复合体和杏仁核之间的连接，可能起着重要作用。锁的外源性和内源性原因之间的差异也可以解释神经性贪食症和神经性厌食症之间的差异。
