可吸收金属（镁）支架的现状。

Current state of the absorbable metallic (magnesium) stent.

机构信息

Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA.

出版信息

EuroIntervention. 2009 Dec 15;5 Suppl F:F94-7. doi: 10.4244/EIJV5IFA16.

DOI:10.4244/EIJV5IFA16

PMID:22100686

Abstract

BIOTRONIK's absorbable metal stent technology is based ona magnesium alloy that offers superior stent mechanics and biocompatibility. The first generation (AMS-1) showed promising results regarding mechanical properties as well as feasibility and safety in several human applications (150 cases). The second generation (AMS-2.1) shows improved scaffolding and efficacy in animals due to a more slowly degrading magnesium alloy and an optimised stent design. The preclinical results of the drug-eluting AMS-3 are encouraging and the clinical investigational program will resume in 2010.

摘要

百多力可吸收金属支架技术基于镁合金，具有优越的支架机械性能和生物相容性。第一代（AMS-1）在机械性能以及数项人体应用的可行性和安全性方面显示出良好的结果（150 例）。第二代（AMS-2.1）由于镁合金降解速度较慢和支架设计得到优化，在动物中显示出改善的支架结构和效果。载药百多力可吸收金属支架的临床前结果令人鼓舞，2010 年将恢复临床研究项目。