枯草芽孢杆菌中 YtnP 的链霉素诱导表达，该蛋白与内酯酶同源，可抑制灰色链霉菌的发育和链霉素的产生。
Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus.
机构信息
Institute for Molecular Infection Biology IMIB, Centre for Molecular Research in Infectious Disease ZINF, University of Würzburg, Würzburg, Germany.
出版信息
Appl Environ Microbiol. 2012 Jan;78(2):599-603. doi: 10.1128/AEM.06992-11. Epub 2011 Nov 18.
Abstract
Bacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus. ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus.
摘要
枯草芽孢杆菌在抗微生物链霉素存在的情况下诱导 ytnP 基因的表达，该链霉素由革兰氏阳性细菌灰色链霉菌产生。ytnP 编码一种内酯酶同源蛋白，能够抑制灰色链霉菌产生链霉素和形成气生菌丝所必需的信号通路。
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本文引用的文献
1
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2
Peptide signaling in the staphylococci.葡萄球菌中的肽信号传导
Chem Rev. 2011 Jan 12;111(1):117-51. doi: 10.1021/cr100370n. Epub 2010 Dec 21.
3
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J Bacteriol. 1946 Sep;52:393-7. doi: 10.1128/JB.52.3.393-397.1946.
4
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J Bacteriol. 1946 Aug;52:223-6. doi: 10.1128/JB.52.2.223-226.1946.
5
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6
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