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择期开腹结直肠手术后转入重症监护病房或外科病房的病例对照研究。

Case-controlled study of critical care or surgical ward care after elective open colorectal surgery.

机构信息

Department of Anaesthesia and Critical Care Medicine, Torbay Hospital, Torquay TQ2 7AA, UK.

出版信息

Br J Surg. 2012 Feb;99(2):295-9. doi: 10.1002/bjs.7789. Epub 2011 Nov 21.

DOI:10.1002/bjs.7789
PMID:22101443
Abstract

BACKGROUND

Evidence for the benefit of critical care after surgery is limited. This study assessed the value of immediate admission to the critical care unit (CCU) after open colorectal surgery.

METHODS

Patients aged over 45 years were screened with a cardiopulmonary exercise test to determine their anaerobic threshold. Less fit patients defined by an anaerobic threshold below 11 ml oxygen per kg per min were assigned to either critical care or surgical ward care. Those with an anaerobic threshold of 11 ml oxygen per kg per min or above were assigned to ward care. The outcome measure was the number of cardiac events.

RESULTS

Of 153 patients who underwent exercise testing, 55 had an anaerobic threshold of at least 11 ml oxygen per kg per min (ward care) and 98 had a threshold of less than 11 ml oxygen per kg per min, of whom 39 were allocated to ward care and 51 to critical care. Median length of CCU stay was 31 (range 5-46) h. More cardiac events occurred in patients allocated to ward care (7 of 39) than in those allocated to critical care (0 of 51): absolute difference 18 (95 per cent confidence interval 10 to 26) per cent (P = 0·002). There were no cardiac events in patients with an anaerobic threshold of 11 ml oxygen per kg per min or higher.

CONCLUSION

Patients with an anaerobic threshold of at least 11 ml oxygen per kg per min and those with a threshold below 11 ml oxygen per kg per min managed in the CCU had fewer cardiac events.

摘要

背景

关于术后重症监护的益处的证据有限。本研究评估了在开腹结直肠手术后立即入住重症监护病房(CCU)的价值。

方法

对年龄超过 45 岁的患者进行心肺运动试验,以确定其无氧阈值。无氧阈值低于 11 ml 氧气/公斤/分钟的患者被分配到 CCU 或外科病房护理。无氧阈值为 11 ml 氧气/公斤/分钟或以上的患者被分配到病房护理。主要结局是心脏事件的数量。

结果

在接受运动测试的 153 名患者中,55 名患者的无氧阈值至少为 11 ml 氧气/公斤/分钟(病房护理),98 名患者的阈值低于 11 ml 氧气/公斤/分钟,其中 39 名被分配到病房护理,51 名被分配到 CCU。CCU 停留时间中位数为 31(5-46)小时。在分配到病房护理的患者(39 例中有 7 例)中发生的心脏事件多于分配到 CCU 护理的患者(51 例中有 0 例):绝对差异为 18%(95%置信区间 10%至 26%)(P=0·002)。无氧阈值为 11 ml 氧气/公斤/分钟或更高的患者没有发生心脏事件。

结论

无氧阈值至少为 11 ml 氧气/公斤/分钟的患者和阈值低于 11 ml 氧气/公斤/分钟的患者在 CCU 中管理的患者心脏事件更少。

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