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面神经副神经节瘤,面神经麻痹的罕见鉴别诊断:病例报告及文献复习。

Paraganglioma of the facial nerve, a rare differential diagnosis for facial nerve paralysis: case report and review of the literature.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Erlangen Medical School, University of Erlangen, Waldstrasse 1, 91054, Erlangen, Germany.

出版信息

Eur Arch Otorhinolaryngol. 2012 Feb;269(2):693-8. doi: 10.1007/s00405-011-1840-3. Epub 2011 Nov 20.

Abstract

This report describes a rare case of histopathologically confirmed glomus facial tumor. The role of imaging in the differential diagnosis is discussed and therapeutic options are evaluated, along with a review of the previous literature on glomus facial tumors. A 39-year-old male patient presented with total peripheral facial nerve paralysis. He underwent radical tumor resection and facial nerve grafting for a histopathologically confirmed paraganglioma of the facial nerve. He is now tumor-free after a 4-year follow-up period, and the functional outcome after primary nerve grafting is satisfactory. Facial nerve paragangliomas are a rare cause of facial nerve paralysis. Early imaging using computed tomography and magnetic resonance imaging is essential to clarify the differential diagnosis and assess the location and extent of the tumor. Precise pathological diagnosis requires additional targeted immunohistochemical examinations. The treatment of choice in patients with preoperative facial nerve paralysis is radical tumor resection with nerve reconstruction.

摘要

本报告描述了一例经组织病理学证实的面部血管球瘤的罕见病例。讨论了影像学在鉴别诊断中的作用,并评估了治疗选择,同时回顾了以往关于面部血管球瘤的文献。一名 39 岁男性患者因外周性面神经麻痹就诊。他因面神经的组织病理学证实为副神经节瘤而行根治性肿瘤切除术和面神经移植术。经过 4 年的随访,患者目前无肿瘤,原发性神经移植后的功能恢复结果满意。面神经副神经节瘤是面神经麻痹的罕见病因。早期使用计算机断层扫描和磁共振成像进行影像学检查对于明确鉴别诊断和评估肿瘤的位置和范围至关重要。精确的病理诊断需要额外的靶向免疫组织化学检查。对于术前存在面神经麻痹的患者,治疗选择是根治性肿瘤切除术加神经重建。

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