The Ohio State University, Columbus, Ohio, USA.
J Magn Reson Imaging. 2011 Dec;34(6):1243-50. doi: 10.1002/jmri.22737.
Acute coronary syndromes (ACS) continue to be the most common morbid condition of industrialized nations. The advent of and technical improvements in revascularization and medical therapy have led to a steady decline in mortality rates. However, many patients who suffer unstable angina or myocardial infarction require further testing and risk stratification to guide therapeutic selection and prognosis assignment. Myocardial edema imaging with cardiac magnetic resonance (CMR) affords the ability to define the amount of myocardium at risk, refine estimates of prognosis and provide guidance for therapies with excellent sensitivity compared with standard clinical markers. This review will discuss the rationale for edema imaging, how it is performed using CMR, and potential clinical applications.
急性冠状动脉综合征(ACS)仍然是工业化国家最常见的病态。再灌注和药物治疗的出现和技术改进导致死亡率稳步下降。然而,许多患有不稳定型心绞痛或心肌梗死的患者需要进一步的检查和风险分层,以指导治疗选择和预后评估。心脏磁共振(CMR)心肌水肿成像能够确定风险心肌的数量,改进预后估计,并与标准临床标志物相比提供治疗指导,具有极好的灵敏度。本文将讨论水肿成像的原理、CMR 成像的方法以及潜在的临床应用。