Scientific Databases and Visualization Group, Heidelberg Institute for Theoretical Studies, gGmbH, Schloss-Wolfsbrunnenweg 35, 69118 Heidelberg, Germany.
Nucleic Acids Res. 2012 Jan;40(Database issue):D790-6. doi: 10.1093/nar/gkr1046. Epub 2011 Nov 18.
SABIO-RK (http://sabio.h-its.org/) is a web-accessible database storing comprehensive information about biochemical reactions and their kinetic properties. SABIO-RK offers standardized data manually extracted from the literature and data directly submitted from lab experiments. The database content includes kinetic parameters in relation to biochemical reactions and their biological sources with no restriction on any particular set of organisms. Additionally, kinetic rate laws and corresponding equations as well as experimental conditions are represented. All the data are manually curated and annotated by biological experts, supported by automated consistency checks. SABIO-RK can be accessed via web-based user interfaces or automatically via web services that allow direct data access by other tools. Both interfaces support the export of the data together with its annotations in SBML (Systems Biology Markup Language), e.g. for import in modelling tools.
SABIO-RK（http://sabio.h-its.org/）是一个可通过网络访问的数据库，用于存储生化反应及其动力学性质的综合信息。SABIO-RK 提供了从文献中手动提取的标准化数据，以及直接从实验室实验中提交的数据。该数据库的内容包括与生化反应及其生物来源有关的动力学参数，且不受任何特定生物体系的限制。此外，还表示了动力学速率定律和相应的方程以及实验条件。所有数据均由生物学专家进行人工整理和注释，并辅以自动一致性检查。SABIO-RK 可通过基于网络的用户界面访问，也可通过允许其他工具直接进行数据访问的网络服务访问。这两个接口都支持以 SBML（系统生物学标记语言）的形式导出数据及其注释，例如，可将其导入建模工具。
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