Lee Byoung Hun, Kwon Jeong-Taik, Park Yong Sook
Department of Neurosurgery, Chung-Ang University College of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2011 Sep;50(3):240-3. doi: 10.3340/jkns.2011.50.3.240. Epub 2011 Sep 30.
Clear cell ependymomas (CCEs) are rare variants of ependymomas. Tumors show anaplastic histological features and behave as an aggressive manner. CCEs have a predilection for extraneural metastases and early recurrence, and they demonstrate characteristic radiographic features. These tumors should be radiologically and pathologically differentiated from oligodendrogliomas. On microscopic examination, CCEs are composed of sheets of cells and resemble oligodendroglioma. However, upon closer examination, the nature of CCEs can be detected earlier, resulting in prompt treatment of the tumor. Although we report only one case, we emphasize the importance of early diagnosis and treatment. Future description of more cases of these rare cancers is necessary to aid in their diagnosis and treatment.
透明细胞室管膜瘤(CCEs)是室管膜瘤的罕见变体。肿瘤呈现间变性组织学特征,并具有侵袭性生长方式。CCEs易发生神经外转移和早期复发,且具有特征性的影像学表现。这些肿瘤应在放射学和病理学上与少突胶质细胞瘤相鉴别。在显微镜检查中,CCEs由成片的细胞组成,类似于少突胶质细胞瘤。然而,经过更仔细的检查,可以更早地发现CCEs的本质,从而对肿瘤进行及时治疗。虽然我们仅报告了1例病例,但我们强调早期诊断和治疗的重要性。未来有必要对更多这些罕见癌症病例进行描述,以辅助其诊断和治疗。