Cunha B A, Gingrich D, Rosenbaum G S
Infectious Disease Division, Winthrop-University Hospital, Mineola, New York.
Geriatrics. 1990 Oct;45(10):49-52, 55.
Important in the pathogenesis of pneumonia in the elderly patient are chronic diseases, including diabetes mellitus, coronary artery disease, congestive heart failure, chronic obstructive pulmonary disease, and cerebrovascular disease. Also vital are the changes that take place in the immune system and mucociliary clearance mechanisms of the lung. The clinician should be aware of these risk factors, especially since the mortality rate of lower respiratory infections approaches 40% in these elderly patients. Treatment guidelines are included.
在老年患者肺炎发病机制中起重要作用的是慢性疾病,包括糖尿病、冠状动脉疾病、充血性心力衰竭、慢性阻塞性肺疾病和脑血管疾病。肺部免疫系统和黏液纤毛清除机制发生的变化也至关重要。临床医生应了解这些危险因素,尤其是因为这些老年患者下呼吸道感染的死亡率接近40%。文中包含了治疗指南。