Milishnikova V V, Loshchilov I U, Gladkova E V, Aksenova A O, Turkina L A
Gig Tr Prof Zabol. 1990(7):19-22.
A bronchofibroscopy study of cases with histologic investigation of the bronchi and pulmonary mucous biopsy of 29 asbestos-textile workers, revealed diffuse bilateral endo-bronchitis (DBE) with concomitant tracheitis at different stages. No correlation was found between the endoscopy pictures and the clinical manifestations of asbestosis and dust bronchitis. The asbestosis diseased patients displayed pulmonary fibrosis++ without granulomatous inflammation in the asbestos dusts zone. In some cases, bronchial epithelium diffuse metaplasia was diagnosed with some dysplasia elements, as well as papillomatosis and malignant tumours in the lungs. Dust bronchitis++ and asbestosis can perform precancerous conditions in the lungs, what should be taken into account in cancer prevention measures for asbestos industry workers.
对29名石棉纺织工人进行支气管镜检查,并对支气管进行组织学检查及肺黏液活检,结果显示不同阶段存在弥漫性双侧支气管炎(DBE)并伴有气管炎。内镜检查结果与石棉沉着病和尘性支气管炎的临床表现之间未发现相关性。石棉沉着病患者在石棉粉尘区域表现为++级肺纤维化,无肉芽肿性炎症。在某些病例中,诊断出支气管上皮弥漫性化生并伴有一些发育异常成分,以及肺部乳头状瘤病和恶性肿瘤。尘性支气管炎++和石棉沉着病可在肺部形成癌前病变,这在石棉行业工人的癌症预防措施中应予以考虑。