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Stain analysis using oligonucleotide probes specific for simple repetitive DNA sequences.

作者信息

Roewer L, Nürnberg P, Fuhrmann E, Rose M, Prokop O, Epplen J T

机构信息

Institut für Gerichtliche Medizin der Humboldt-Universität zu Berlin, GDR.

出版信息

Forensic Sci Int. 1990 Aug;47(1):59-70. doi: 10.1016/0379-0738(90)90285-7.

Abstract

The use of oligonucleotide fingerprinting is evaluated in practical forensic work, using both artificially and systematically produced stains as well as actual case work material. The probes (CAC5/(GTG)5 are superior because of their individualizing potential in comparatively fresh specimens with little DNA degradation, whereas (GACA)4, still produces substantial information when high molecular weight DNA is lacking. The overall limitations and the advantages of this technology are discussed in detail and compared to the classical minisatellite probes.

摘要

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