Chronic anterior uveitis in common variable immunodeficiency.

PURPOSE

To describe patients with uveitis and common variable immunodeficiency (CVID).

DESIGN

Retrospective observational case series.

METHODS

Retrospective review of patients with uveitis and CVID, specifically focusing on clinical presentation and treatment.

RESULTS

Three patients with CVID and uveitis were identified. All patients had chronic anterior uveitis. Two required systemic immunosuppression to control uveitis, with one of these patients relapsing after discontinuation of immunoglobulin therapy. One improved on topical steroid therapy; however, follow-up on this patient did not extend beyond 4 months.

CONCLUSIONS

CVID can be associated with chronic anterior uveitis. Patients presenting with uveitis should be questioned about frequent infections and autoimmune disorders as part of the uveitis evaluation.