三维定量冠状动脉造影术。

Three-dimensional quantitative coronary angiography.

作者信息

Saito T, Misaki M, Shirato K, Takishima T

机构信息

Institute of Information Sciences and Electronics, University of Tsukuba, Japan.

出版信息

IEEE Trans Biomed Eng. 1990 Aug;37(8):768-77. doi: 10.1109/10.102792.

DOI:10.1109/10.102792

PMID:2210785

Abstract

A method for reconstructing the three-dimensional coronary arterial tree structure from biplane two-dimensional angiographic images is presented. This method exploits the geometrical mathematics of X-ray imaging and the tracking of leading edges of injected contrast material into each vessel for identification of corresponding points on two images taken from orthogonal views. Accurate spatial position and dimension of each vessel in three-dimensional space can be obtained by this reconstruction procedure. The reconstructed arterial configuration is displayed as a shaded surface model, which can be viewed from various angles. Such three-dimensional vascular information provides accurate and reproducible measurements of vascular morphology and function. Flow measurements are obtained by tracking the leading edge of contrast material down the three-dimensional arterial tree. A quantitative analysis of coronary stenosis based on transverse area narrowing and regional blood flow, including the effect of vasoactive drugs, is described. Reconstruction experiments on actual angiographic images of the human coronary artery yield encouraging results toward a realization of computer-assisted three-dimensional quantitative angiography.

摘要

本文提出了一种从双平面二维血管造影图像重建三维冠状动脉树结构的方法。该方法利用了X射线成像的几何数学原理，并通过跟踪注入造影剂在每个血管中的前缘来识别从正交视图获取的两张图像上的对应点。通过这种重建过程，可以获得三维空间中每个血管的准确空间位置和尺寸。重建的动脉结构以阴影表面模型显示，可以从各个角度查看。这种三维血管信息提供了血管形态和功能的准确且可重复的测量。通过跟踪造影剂在三维动脉树中的前缘来获得流量测量值。描述了基于横截面积变窄和局部血流，包括血管活性药物作用的冠状动脉狭窄定量分析。对人类冠状动脉实际血管造影图像的重建实验朝着实现计算机辅助三维定量血管造影取得了令人鼓舞的结果。