Camargo P R, Mazzieri R, Snitcowsky R, Higuchi M L, Meneghetti J C, Soares Júnior J, Fiorelli A, Ebaid M, Pileggi F
Heart Institute, University of São Paulo Medical School, Brazil.
Int J Cardiol. 1990 Sep;28(3):293-7. doi: 10.1016/0167-5273(90)90311-r.
Fourty-four patients (aged 10 months to 15 years) were assessed in a double-blind study to observe the correlation between myocardial uptake of 67-gallium and endomyocardial biopsy in the detection of moderate to severe myocardial inflammation. The sensitivity and specificity of gallium-67 imaging were 87 and 81%, respectively. Based on these findings, immunosuppressive therapy can be assigned to children with dilated cardiomyopathy and positive myocardial uptake, since moderate and severe myocardial inflammation may be detected by this non-invasive method.
在一项双盲研究中，对44例年龄在10个月至15岁之间的患者进行了评估，以观察67镓心肌摄取与心内膜心肌活检在检测中度至重度心肌炎症中的相关性。67镓成像的敏感性和特异性分别为87%和81%。基于这些发现，对于扩张型心肌病且心肌摄取呈阳性的儿童可给予免疫抑制治疗，因为通过这种非侵入性方法可能检测到中度和重度心肌炎症。
