从过氧化微粒体获得的一种脂质材料的溶血活性。
Hemolytic activity of a lipid material obtained from peroxidized microsomes.
作者信息
Willis R J, Pesh-Imam M, Recknagel R O
出版信息
Res Commun Chem Pathol Pharmacol. 1977 Nov;18(3):433-7.
PMID:22110
Abstract
Lipid peroxidation was induced in rat liver microsomes by the addition of NADPH. When mixed with red cells in the presence of EDTA, these peroxidized microsomes caused hemolysis. All of the hemolytic activity of peroxidized microsomes could be extracted with lipid solvents and recovered as an aqueous lipid emulsion.
摘要
通过添加NADPH在大鼠肝脏微粒体中诱导脂质过氧化。当在EDTA存在下与红细胞混合时，这些过氧化的微粒体导致溶血。过氧化微粒体的所有溶血活性都可以用脂质溶剂提取，并作为水性脂质乳剂回收。
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