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一名高钙尿症儿童中与头孢曲松相关的尿路结石

Ceftriaxone associated urolithiasis in a child with hypercalciuria.

作者信息

Lozanovski V J, Gucev Z, Avramoski V J, Kirovski I, Makreski P, Tasic V

出版信息

Hippokratia. 2011 Apr;15(2):181-3.

PMID:22110305
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3209686/
Abstract

We present a 5-year-old boy with pneumonia who complained of right lumbar pain on the 7(th) day of treatment with Ceftriaxone. Ultrasound examination revealed mild to moderate right hydronephrosis. Under spasmoanalgetic therapy and hydration there was spontaneous passage of three small calculi. Infrared spectroscopy showed that the calculi were composed of calcium-ceftriaxonate. Full metabolic investigation was performed and moderate hypercalciuria was detected, suggesting the role of hypercalciuria in ceftriaxone-associated nephrolithiasis.

摘要

我们报告一名5岁患肺炎的男孩,在接受头孢曲松治疗第7天时出现右腰疼痛。超声检查显示右肾轻度至中度积水。在解痉镇痛治疗和补液后,有3枚小结石自行排出。红外光谱显示结石由头孢曲松钙组成。进行了全面的代谢检查,检测到中度高钙尿症,提示高钙尿症在头孢曲松相关肾结石形成中的作用。

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本文引用的文献

1
Nephrolithiasis caused by ceftriaxone in a 3-year-old child with ureteropelvic junction obstruction.一名3岁输尿管肾盂连接处梗阻患儿因头孢曲松导致肾结石。
Case Rep Med. 2009;2009:365962. doi: 10.1155/2009/365962. Epub 2009 May 26.
2
Ceftriaxone associated nephrolithiasis: a prospective study in 284 children.头孢曲松相关肾结石:对284名儿童的前瞻性研究。
Pediatr Nephrol. 2007 May;22(5):690-4. doi: 10.1007/s00467-006-0401-2. Epub 2007 Jan 17.
3
Ceftriaxone-associated biliary pseudolithiasis in children.儿童头孢曲松相关的胆汁假性结石形成
J Clin Ultrasound. 2006 Jun;34(5):217-22. doi: 10.1002/jcu.20228.
4
Nephrolithiasis in a child with acute pyelonephritis. Ceftriaxone-induced nephrolithiasis and biliary pseudolithiasis.一名患有急性肾盂肾炎儿童的肾结石。头孢曲松诱导的肾结石和胆假性结石。
Pediatr Nephrol. 2005 Oct;20(10):1510-1, 1512-3. doi: 10.1007/s00467-005-1909-6. Epub 2005 Aug 5.
5
Nephrolithiasis associated with ceftriaxone therapy: a prospective study in 51 children.头孢曲松治疗相关的肾结石:51例儿童的前瞻性研究
Arch Dis Child. 2004 Nov;89(11):1069-72. doi: 10.1136/adc.2003.044156.
6
Ceftriaxone-associated biliary sludge and pseudocholelithiasis during childhood: a prospective study.儿童期头孢曲松相关的胆泥和假性胆石症:一项前瞻性研究。
Pediatr Int. 2004 Jun;46(3):322-4. doi: 10.1111/j.1328-0867.2004.01884.x.
7
Gallbladder and urinary tract precipitations associated with ceftriaxone therapy in children: a prospective study.儿童头孢曲松治疗相关的胆囊和泌尿道沉淀物:一项前瞻性研究。
Ann Trop Paediatr. 2004 Mar;24(1):25-31. doi: 10.1179/027249304225013349.
8
Drug-induced renal calculi: epidemiology, prevention and management.药物性肾结石:流行病学、预防与管理
Drugs. 2004;64(3):245-75. doi: 10.2165/00003495-200464030-00003.
9
Ceftriaxone-associated nephrolithiasis and biliary pseudolithiasis in a child.一名儿童中与头孢曲松相关的肾结石和胆假性结石
Pediatr Radiol. 2003 Sep;33(9):648-51. doi: 10.1007/s00247-003-0963-0. Epub 2003 Jun 26.
10
Early biliary pseudolithiasis during ceftriaxone therapy for acute pyelonephritis in children: a prospective study in 34 children.儿童急性肾盂肾炎头孢曲松治疗期间早期胆假性结石形成:34例儿童的前瞻性研究
Eur J Pediatr Surg. 2000 Dec;10(6):368-71. doi: 10.1055/s-2008-1072393.