Department of Psychiatry, Walter Reed Army Medical Center, Washington, DC, USA.
Psychol Res Behav Manag. 2010;3:109-18. doi: 10.2147/PRBM.S10035. Epub 2010 Dec 6.
Poststroke depression (PSD) is a common sequela of stroke associated with increased morbidity and mortality among stroke survivors. PSD has been associated with poorer rehabilitative outcomes, longer inpatient stays, inefficient use of medical resources, worsened cognitive decline, and increased suicidality. This article reviews the definition and proposed etiology of PSD as well as current and emerging evidence-based prevention, screening, and treatment modalities. The timely use of prevention and treatment techniques including pharmacologic and nonpharmacologic methods may improve treatment outcomes and enhance the quality of life in stroke patients.
脑卒中后抑郁(PSD)是脑卒中的常见后遗症,与脑卒中幸存者的发病率和死亡率增加有关。PSD 与康复效果较差、住院时间延长、医疗资源利用效率低下、认知能力下降恶化以及自杀风险增加有关。本文回顾了 PSD 的定义和提出的病因,以及当前和新兴的基于证据的预防、筛查和治疗方法。及时使用预防和治疗技术,包括药物和非药物方法,可能改善治疗效果并提高脑卒中患者的生活质量。