Annoni Jean-Marie, Staub Fabienne, Bogousslavsky Julien, Brioschi Andrea
Neurological Department, Lausanne University Hospital and Medical School, 1011, Lausanne, Switzerland.
Neurol Sci. 2008 Sep;29 Suppl 2:S244-6. doi: 10.1007/s10072-008-0951-0.
Post-stroke objective or subjective fatigue occurs in around 50% of patients and is frequent (30%) even after minor strokes. It can last more than one year after the event, and is characterised by a different quality from usual fatigue and good response to rest. Associated risk factors include age, single patients, female, disability, depression, attentional impairment and sometimes posterior strokes, but also inactivity, overweight, alcohol and sleep apnoea syndrome. There are few therapy studies, but treatment may include low-intensity training, cognitive therapy, treatment of associated depression, wakefulness-promoting agents like modafinil, correction of risk factors and adaptation of activities.
中风后客观或主观疲劳发生在约50%的患者中，即使是轻微中风后也很常见（30%）。它可能在中风事件后持续一年以上，其特点是与通常的疲劳性质不同，对休息反应良好。相关风险因素包括年龄、单身患者、女性、残疾、抑郁、注意力障碍，有时还包括后循环中风，以及缺乏运动、超重、酗酒和睡眠呼吸暂停综合征。治疗研究很少，但治疗可能包括低强度训练、认知疗法、治疗相关抑郁、使用如莫达非尼等促醒药物、纠正风险因素以及调整活动。
