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前列腺癌根治术后直肠膀胱瘘:关于发病率、病因及治疗的文献综述

Rectourinary fistula after radical prostatectomy: review of the literature for incidence, etiology, and management.

作者信息

Kitamura Hiroshi, Tsukamoto Taiji

机构信息

Department of Urology, Sapporo Medical University School of Medicine, South 1 West 16, Chuo-ku, Sapporo 060-8543, Japan.

出版信息

Prostate Cancer. 2011;2011:629105. doi: 10.1155/2011/629105. Epub 2011 Jan 26.

Abstract

Although rectourinary fistula (RUF) after radical prostatectomy (RP) is rare, it is an important issue impairing the quality of life of patients. If the RUF does not spontaneously close after colostomy, surgical closure should be considered. However, there is no standard approach and no consensus in the literature. A National Center for Biotechnology Information (NVBI) PubMed search for relevant articles published between 1995 and December 2010 was performed using the medical subject headings "radical prostatectomy" and "fistula." Articles relevant to the treatment of RUF were retained. RUF developed in 0.6% to 9% of patients after RP. Most cases required colostomy, but more than 50% of them needed surgical fistula closure thereafter. The York-Mason technique is the most common approach, and closure using a broad-based flap of rectal mucosa is recommended after excision of the RUF. New techniques using a sealant or glue are developing, but further successful reports are needed.

摘要

尽管前列腺癌根治术(RP)后直肠尿道瘘(RUF)较为罕见,但却是一个影响患者生活质量的重要问题。如果结肠造口术后RUF未自行闭合,则应考虑手术闭合。然而,目前尚无标准方法,且文献中也未达成共识。利用医学主题词“前列腺癌根治术”和“瘘”,在美国国立生物技术信息中心(NCBI)的PubMed数据库中检索了1995年至2010年12月期间发表的相关文章。保留了与RUF治疗相关的文章。RP术后0.6%至9%的患者发生RUF。大多数病例需要结肠造口术,但其中超过50%的患者此后需要手术闭合瘘管。约克-梅森技术是最常用的方法,建议在切除RUF后使用宽基底直肠黏膜瓣进行闭合。使用密封剂或胶水的新技术正在研发中,但还需要更多成功的报道。

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