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马来西亚吉隆坡生殖因素和家族史对绝经前乳腺癌风险的影响

The contribution of reproductive factors and family history towards premenopausal breast cancer risk in Kuala Lumpur, Malaysia.

作者信息

Razif S Mohd, Sulaiman S, Hanie S Soraya, Aina E Nor, Rohaizak M, Fuad I, Nurismah M I, Sharifah N A

机构信息

Department of Nutrition and Dietetics, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

出版信息

Med J Malaysia. 2011 Aug;66(3):220-6.

PMID:22111444
Abstract

Breast cancer is the most common cancer among Malaysian women. This study aimed to determine the reproductive for premenopausal breast cancer risk in Kuala Lumpur, Malaysia. A case-control study was conducted in 216 histopathologically confirmed cases of premenopausal breast cancer and 216 community-based controls that were matched by age within a 5-year period and ethnicity. The results of this study showed that premenopausal breast cancer risks were strongly related to parity, number of live births and family history of breast cancer. Premenopausal women with these known reproductive and family history risk factors should take extra measures to undergo appropriate screening method for early detection of breast cancer.

摘要

乳腺癌是马来西亚女性中最常见的癌症。本研究旨在确定马来西亚吉隆坡绝经前乳腺癌风险的生殖因素。对216例经组织病理学确诊的绝经前乳腺癌病例和216名社区对照者进行了一项病例对照研究,这些对照者在年龄上在5年内匹配且种族相同。本研究结果表明,绝经前乳腺癌风险与产次、活产数和乳腺癌家族史密切相关。有这些已知生殖和家族史风险因素的绝经前女性应采取额外措施,接受适当的筛查方法以早期发现乳腺癌。

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