Department of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong.
J Eval Clin Pract. 2012 Dec;18(6):1203-10. doi: 10.1111/j.1365-2753.2011.01776.x. Epub 2011 Nov 23.
To estimate the direct medical cost of colorectal neoplasia (CRN) from newly diagnosed to the completion of the tumour-specific treatment in the initial year of disease across stages and tumour primary sites.
Only direct medical costs from the perspective of the health care service provider were incorporated in the cost analysis (in 2009 USD) using a bottom-up approach. Tumour-specific treatments of surgery, chemotherapy and radiotherapy data in the initial year of disease were identified from the 401 CRN adult patients by a review of their medical records. Service utilization for diagnosis, staging, pre-operative assessment and post-operative follow-up consultations was estimated from the recommendations of established surveillance and clinical practice guidelines.
Direct medical cost for the care of a newly diagnosed CRN was ranging from $1941 for low-risk polyp to $45 115 for stage IV colorectal cancer in the initial year of care. Costs of care showed a gradient increase from $1748 for low-risk colonic polyps to $42 899 for stage IV colon cancer, and from $2232 for low-risk rectal polyps to $48 453 for stage IV rectal cancers. Diagnostic/pre-operative assessment and treatment accounted for most of total costs of colorectal polyp (58.9-76.7%) and cancer (60.8-85.2%) care.
The results provided stage and site-specific estimations of the direct medical costs of CRN in a Chinese population that can assist policy decision making and facilitate health care service planning and cost-effectiveness evaluations.
估算各期和肿瘤原发部位结直肠肿瘤(CRN)从初诊到肿瘤特异性治疗完成的直接医疗成本。
本成本分析仅纳入医疗服务提供者视角的直接医疗成本(2009 年美元),采用自下而上的方法。通过回顾病历,从 401 例 CRN 成年患者中确定初诊年内肿瘤特异性治疗(手术、化疗和放疗)的数据。根据既定监测和临床实践指南的建议,估算诊断、分期、术前评估和术后随访咨询的服务利用情况。
初诊 CRN 患者的医疗费用在 1941 美元(低危息肉)至 45115 美元(IV 期结直肠癌)之间。从低危结肠息肉的 1748 美元到 IV 期结肠癌的 42899 美元,以及从低危直肠息肉的 2232 美元到 IV 期直肠癌的 48453 美元,成本呈梯度增加。诊断/术前评估和治疗占结直肠息肉(58.9%-76.7%)和癌症(60.8%-85.2%)治疗总费用的大部分。
本研究结果为中国人群结直肠肿瘤的直接医疗成本提供了基于分期和部位的估计,可协助制定政策决策,并促进医疗服务规划和成本效益评估。