Alefan Qais, Malhees Rana, Mhaidat Nizar
Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Curr Probl Cancer. 2017 Sep-Oct;41(5):371-381. doi: 10.1016/j.currproblcancer.2017.05.001. Epub 2017 May 15.
Colorectal cancer (CRC) is mainly characterized as the malignant and impaired growth of rectal cells in the intestinal region. Direct medical cost is related to resources, which are directly used in treating the patient, that mainly includes the cost of drugs, diagnostic, treatment, follow-up, rehabilitation, and hospital admission. The objective of this study is to estimate and analyze direct medical costs attributable to CRC in Jordan. A retrospective analysis of a cohort patients treated for CRC data has been performed to determine direct medical costs attributable to CRC in Jordan. The prevalence-based approach has been used in addition to the "bottom up" approach to accumulate 1-year time costs of CRC. Demographic, clinical, and economic data have been collected and analyzed using SPSS for windows. Costs were estimated by a bottom-up approach, in which each service component was identified and valued at the most detailed level, to provide greater transparency and reliability in economic evaluation of health care services. This study quantified the economic burden associated with CRC by Jordanian patients in King Abdullah University Hospital from the perspective of health care providers (public sector). Total CRC cost in the year 2014 was estimated to JD 695,608, and the most expensive stage for all sites was stage 4 reaching a cost of JD 5147. Advanced disease stages were associated with an increase in total cost and chemotherapy costs. In conclusion, results of this study propose that direct medical costs associated with CRC are considerable. Most of the cost was devoted for medications, primarily chemotherapy. Advanced stages were associated with higher cost and largest number of patients.
结直肠癌(CRC)主要表现为肠道区域直肠细胞的恶性和异常生长。直接医疗成本与直接用于治疗患者的资源相关,主要包括药物、诊断、治疗、随访、康复和住院费用。本研究的目的是估计和分析约旦CRC的直接医疗成本。已对一组接受CRC治疗的患者数据进行回顾性分析,以确定约旦CRC的直接医疗成本。除了“自下而上”的方法外,还采用了基于患病率的方法来累积CRC的1年时间成本。使用SPSS for windows收集和分析了人口统计学、临床和经济数据。成本通过自下而上的方法进行估计,其中每个服务组件都在最详细的层面进行识别和估值,以便在医疗保健服务的经济评估中提供更高的透明度和可靠性。本研究从医疗保健提供者(公共部门)的角度量化了约旦阿卜杜拉国王大学医院患者与CRC相关的经济负担。2014年CRC的总成本估计为695,608约旦第纳尔,所有部位最昂贵的阶段是4期,成本达到5147约旦第纳尔。疾病晚期与总成本和化疗成本的增加相关。总之,本研究结果表明,与CRC相关的直接医疗成本相当可观。大部分成本用于药物,主要是化疗。晚期与更高的成本和最多的患者数量相关。