有氧运动对 2 型糖尿病患者某些生理参数和生活质量的影响。
Effects of aerobic exercise on selected physiological parameters and quality of life in patients with type 2 diabetes mellitus.
机构信息
Department of Physiotherapy, School of Allied Health Sciences, College of Health Sciences, Accra, University of Ghana, Accra, Ghana.
出版信息
Int J Gen Med. 2011;4:723-7. doi: 10.2147/IJGM.S16717. Epub 2011 Oct 26.
BACKGROUND
The aim of this study was to evaluate the effects of an 8-week aerobic exercise program on physiological parameters and quality of life in patients with type 2 diabetes mellitus.
METHODS
Patients attending a diabetes clinic participated in this randomized control trial. They were randomly assigned to an intervention or control group by ballot. The intervention group, in addition to regular conventional treatment, received individually prescribed aerobic exercise for 30 minutes, at 50%-75% of maximum heart rate three times weekly. Main outcome measures included fasting blood sugar, glycosylated hemoglobin (HbA(1c)), high-density lipoprotein, low-density lipoprotein, and a World Health Organization quality of life questionnaire (WHOQoL-BREF). Data analysis involved paired and unpaired t-tests and mixed-design two-way analysis of variance.
RESULTS
Eighteen patients with type 2 diabetes and of mean age 46.22 ± 9.79 years participated in the study. Mean duration since onset of diabetes in the intervention and control groups was 4.44 ± 3.33 years and 3.92 ± 2.66 years, respectively. Both groups were similar for duration since onset, baseline physiological parameters, and quality of life. Within-group comparison did not show any significant differences (P > 0.05) for HbA(1c), fasting blood sugar, low-density lipoprotein, or high-density lipoprotein. The intervention group improved significantly (P < 0.05) in their postexercise quality of life compared with baseline. Between-group comparison did not show any significant differences in physiological parameters or quality of life.
CONCLUSION
Patients with type 2 diabetes improved in fasting blood sugar, low-density lipoprotein, high-density lipoprotein, and quality of life following 8 weeks of aerobic exercise training. These perceived improvements were not reflected by statistically significant differences in between-group comparison for any parameters.
背景
本研究旨在评估 8 周有氧运动方案对 2 型糖尿病患者生理参数和生活质量的影响。
方法
参加糖尿病门诊的患者参与了这项随机对照试验。他们通过抽签被随机分配到干预组或对照组。干预组除了常规的常规治疗外，还接受了个体化的 30 分钟有氧运动，运动强度为最大心率的 50%-75%，每周 3 次。主要观察指标包括空腹血糖、糖化血红蛋白（HbA1c）、高密度脂蛋白、低密度脂蛋白和世界卫生组织生活质量问卷（WHOQoL-BREF）。数据分析涉及配对和非配对 t 检验以及混合设计双向方差分析。
结果
18 名年龄 46.22 ± 9.79 岁的 2 型糖尿病患者参与了本研究。干预组和对照组的糖尿病发病时间分别为 4.44 ± 3.33 年和 3.92 ± 2.66 年。两组的发病时间、基线生理参数和生活质量均相似。组内比较在 HbA1c、空腹血糖、低密度脂蛋白或高密度脂蛋白方面均无显著差异（P > 0.05）。与基线相比，干预组在运动后的生活质量方面有显著改善（P < 0.05）。组间比较在生理参数或生活质量方面无显著差异。
结论
2 型糖尿病患者在进行 8 周有氧运动训练后，空腹血糖、低密度脂蛋白、高密度脂蛋白和生活质量均有所改善。这些感知到的改善在组间比较中没有统计学意义。
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