糖尿病患者的空腹血糖和血脂水平通过有氧运动训练得到改善。

Fasting plasma glucose and lipid profiles of diabetic patients improve with aerobic exercise training.

作者信息

Asuako Benjamin, Moses Monday O, Eghan Benjamin A, Sarpong Peter A

机构信息

Department of Sports and Exercise Science, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Diabetes Clinic Unit, Department of Medicine, Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.

出版信息

Ghana Med J. 2017 Sep;51(3):120-127. doi: 10.4314/gmj.v51i3.5.

DOI:10.4314/gmj.v51i3.5

PMID:29622823

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5870228/

Abstract

OBJECTIVE

This study presents the effects of aerobic exercise training on fasting plasma glucose and lipid profiles (FPG/LP) of diabetic patients in Kumasi.

DESIGN

A randomised experimental with control design.

SETTING

The study was conducted at the diabetic unit of KATH in Kumasi, Ghana.

PARTICIPANTS

Twelve diabetic patients [grouped into intervention (IG) and control (CG)] attending the diabetic unit of KATH with diabetes diagnosis durations less than fifty years, ambulant status/age of 20-68years, sedentary and free from complications.

INTERVENTIONS

Eight weeks aerobic exercise training between August 2015 and March 2016.

MAIN OUTCOME MEASURES

Body weight (BW), Body mass index (BMI), fasting plasma glucose (FPG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglycerides (T) and total cholesterol (TC).

RESULTS

Body weight (4.85kg, 7.0%), body mass index (4.08kg/m, 7.3%), FPG (5.28mmol/L, 43.5%), LDL-C (.33mmol/l, 11.9%), TC (.47 mmol/l, 5.3%) and T (.48mmol/l, 29.4%) profiles of the patients in IG declined while HDL-C (.11mmol/l, 7.1%) increased. IG patients improved significantly in FPG [6.27 ± 0.91 < 8.00 ± 0.96; t=-52.00, P = 0.000], BW [58.60 ± 15.34 < 75.35 ± 22.00; t= 3.29, P = 0.040] and BMI [23.45 ±5.03<27.04 ±4.78, t=4.24, P = .050] compared to CG.

CONCLUSION

Patients in IG, in addition to conventional care, experienced non-significant decline in LDL-C, TC, T, increase in HDL-C and significant reduction in FPG, BW, and BMI over those receiving conventional care only. Exercise Scientists are recommended to handle exercise sessions for healthcare prevention and management routines of diabetic patients.

FUNDING

Not declared.

摘要

目的

本研究呈现了有氧运动训练对库马西糖尿病患者空腹血糖和血脂谱（FPG/LP）的影响。

设计

随机对照实验设计。

地点

该研究在加纳库马西KATH糖尿病科进行。

参与者

12名糖尿病患者[分为干预组（IG）和对照组（CG）]，就诊于KATH糖尿病科，糖尿病诊断时长小于50年，可独立行走，年龄在20 - 68岁之间，久坐不动且无并发症。

干预措施

2015年8月至2016年3月期间进行为期八周的有氧运动训练。

主要观察指标

体重（BW）、体重指数（BMI）、空腹血糖（FPG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（T）和总胆固醇（TC）。

结果

干预组患者的体重（4.85kg，7.0%）、体重指数（4.08kg/m，7.3%）、空腹血糖（5.28mmol/L，43.5%）、低密度脂蛋白胆固醇（.33mmol/l，11.9%）、总胆固醇（.47 mmol/l，5.3%）和甘油三酯（.48mmol/l，29.4%）水平下降，而高密度脂蛋白胆固醇（.11mmol/l，7.1%）升高。与对照组相比，干预组患者的空腹血糖[6.27 ± 0.91 < 8.00 ± 0.96；t = -52.00，P = 0.000]、体重[58.60 ± 15.34 < 75.35 ± 22.00；t = 3.29，P = 0.040]和体重指数[23.45 ± 5.03 < 27.04 ± 4.78，t = 4.24，P =.050]有显著改善。