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1
Minicell-forming mutants of Escherichia coli: suppression of both DicB- and MinD-dependent division inhibition by inactivation of the minC gene product.大肠杆菌的小细胞形成突变体：通过使minC基因产物失活来抑制DicB和MinD依赖性的分裂抑制
J Bacteriol. 1990 Oct;172(10):5852-5. doi: 10.1128/jb.172.10.5852-5855.1990.
2
Central role for the Escherichia coli minC gene product in two different cell division-inhibition systems.大肠杆菌minC基因产物在两种不同的细胞分裂抑制系统中的核心作用。
Proc Natl Acad Sci U S A. 1990 Feb;87(3):1129-33. doi: 10.1073/pnas.87.3.1129.
3
New minC mutations suggest different interactions of the same region of division inhibitor MinC with proteins specific for minD and dicB coinhibition pathways.新的minC突变表明，分裂抑制剂MinC同一区域与minD和dicB共抑制途径特异性蛋白之间存在不同的相互作用。
J Bacteriol. 1992 Jan;174(1):35-9. doi: 10.1128/jb.174.1.35-39.1992.
4
A division inhibitor and a topological specificity factor coded for by the minicell locus determine proper placement of the division septum in E. coli.一种分裂抑制剂和由微细胞基因座编码的拓扑特异性因子决定了大肠杆菌中分裂隔膜的正确定位。
Cell. 1989 Feb 24;56(4):641-9. doi: 10.1016/0092-8674(89)90586-2.
5
MinC mutants deficient in MinD- and DicB-mediated cell division inhibition due to loss of interaction with MinD, DicB, or a septal component.MinC突变体因与MinD、DicB或隔膜成分失去相互作用而缺乏MinD和DicB介导的细胞分裂抑制作用。
J Bacteriol. 2005 Apr;187(8):2846-57. doi: 10.1128/JB.187.8.2846-2857.2005.
6
Isolation and mapping of Escherichia coli mutations conferring resistance to division inhibition protein DicB.对赋予抗分裂抑制蛋白DicB抗性的大肠杆菌突变体进行分离和定位。
J Bacteriol. 1989 Aug;171(8):4315-9. doi: 10.1128/jb.171.8.4315-4319.1989.
7
Targeting of (D)MinC/MinD and (D)MinC/DicB complexes to septal rings in Escherichia coli suggests a multistep mechanism for MinC-mediated destruction of nascent FtsZ rings.在大肠杆菌中，（D）MinC/MinD和（D）MinC/DicB复合物靶向隔膜环，这表明MinC介导新生FtsZ环破坏的机制是多步骤的。
J Bacteriol. 2002 Jun;184(11):2951-62. doi: 10.1128/JB.184.11.2951-2962.2002.
8
Identification and sequence of gene dicB: translation of the division inhibitor from an in-phase internal start.基因dicB的鉴定与序列：来自同相位内部起始的分裂抑制剂的翻译
Nucleic Acids Res. 1988 Jul 25;16(14A):6327-38. doi: 10.1093/nar/16.14.6327.
9
Cryptic-Prophage-Encoded Small Protein DicB Protects from Phage Infection by Inhibiting Inner Membrane Receptor Proteins.隐匿性噬菌体编码的小蛋白 DicB 通过抑制内膜受体蛋白来保护免受噬菌体感染。
J Bacteriol. 2019 Nov 5;201(23). doi: 10.1128/JB.00475-19. Print 2019 Dec 1.
10
Roles of MinC and MinD in the site-specific septation block mediated by the MinCDE system of Escherichia coli.MinC和MinD在大肠杆菌MinCDE系统介导的位点特异性隔膜形成阻断中的作用。
J Bacteriol. 1992 Jan;174(1):63-70. doi: 10.1128/jb.174.1.63-70.1992.

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1
Robust and resource-optimal dynamic pattern formation of Min proteins in vivo.Min蛋白在体内强大且资源优化的动态模式形成。
Nat Phys. 2025;21(7):1160-1169. doi: 10.1038/s41567-025-02878-w. Epub 2025 May 5.
2
Cryptic-Prophage-Encoded Small Protein DicB Protects from Phage Infection by Inhibiting Inner Membrane Receptor Proteins.隐匿性噬菌体编码的小蛋白 DicB 通过抑制内膜受体蛋白来保护免受噬菌体感染。
J Bacteriol. 2019 Nov 5;201(23). doi: 10.1128/JB.00475-19. Print 2019 Dec 1.
3
MinC N- and C-Domain Interactions Modulate FtsZ Assembly, Division Site Selection, and MinD-Dependent Oscillation in .MinC N- 和 C-结构域相互作用调节 FtsZ 组装、分裂位点选择和 MinD 依赖性振荡。
J Bacteriol. 2019 Jan 28;201(4). doi: 10.1128/JB.00374-18. Print 2019 Feb 15.
4
A Prophage-Encoded Small RNA Controls Metabolism and Cell Division in .一种原噬菌体编码的小RNA控制……中的代谢和细胞分裂。
mSystems. 2016 Feb 9;1(1). doi: 10.1128/mSystems.00021-15. eCollection 2016 Jan-Feb.
5
The CnuK9E H-NS complex antagonizes DNA binding of DicA and leads to temperature-dependent filamentous growth in E. coli.CnuK9E H-NS 复合物拮抗 DicA 的 DNA 结合，并导致大肠杆菌中温度依赖性的丝状生长。
PLoS One. 2012;7(9):e45236. doi: 10.1371/journal.pone.0045236. Epub 2012 Sep 13.
6
MinC mutants deficient in MinD- and DicB-mediated cell division inhibition due to loss of interaction with MinD, DicB, or a septal component.MinC突变体因与MinD、DicB或隔膜成分失去相互作用而缺乏MinD和DicB介导的细胞分裂抑制作用。
J Bacteriol. 2005 Apr;187(8):2846-57. doi: 10.1128/JB.187.8.2846-2857.2005.
7
Conserved glycines in the C terminus of MinC proteins are implicated in their functionality as cell division inhibitors.MinC蛋白C末端保守的甘氨酸与其作为细胞分裂抑制剂的功能有关。
J Bacteriol. 2004 May;186(9):2841-55. doi: 10.1128/JB.186.9.2841-2855.2004.
8
ZipA is required for targeting of DMinC/DicB, but not DMinC/MinD, complexes to septal ring assemblies in Escherichia coli.ZipA是大肠杆菌中DMinC/DicB复合物而非DMinC/MinD复合物靶向隔膜环组装所必需的。
J Bacteriol. 2004 Apr;186(8):2418-29. doi: 10.1128/JB.186.8.2418-2429.2004.
9
Membrane localization of MinD is mediated by a C-terminal motif that is conserved across eubacteria, archaea, and chloroplasts.MinD的膜定位由一个C端基序介导，该基序在真细菌、古细菌和叶绿体中保守。
Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15693-8. doi: 10.1073/pnas.232590599. Epub 2002 Nov 7.
10
Targeting of (D)MinC/MinD and (D)MinC/DicB complexes to septal rings in Escherichia coli suggests a multistep mechanism for MinC-mediated destruction of nascent FtsZ rings.在大肠杆菌中，（D）MinC/MinD和（D）MinC/DicB复合物靶向隔膜环，这表明MinC介导新生FtsZ环破坏的机制是多步骤的。
J Bacteriol. 2002 Jun;184(11):2951-62. doi: 10.1128/JB.184.11.2951-2962.2002.

本文引用的文献

1
MINIATURE escherichia coli CELLS DEFICIENT IN DNA.DNA缺陷的微小大肠杆菌细胞
Proc Natl Acad Sci U S A. 1967 Feb;57(2):321-6. doi: 10.1073/pnas.57.2.321.
2
Establishing homologies in protein sequences.确定蛋白质序列中的同源性。
Methods Enzymol. 1983;91:524-45. doi: 10.1016/s0076-6879(83)91049-2.
3
Genetic basis of minicell formation in Escherichia coli K-12.大肠杆菌K-12中微小细胞形成的遗传基础。
J Bacteriol. 1984 Jun;158(3):1202-3. doi: 10.1128/jb.158.3.1202-1203.1984.
4
Genetic mapping of the minB locus in Escherichia coli K-12.大肠杆菌K-12中minB基因座的遗传图谱
J Bacteriol. 1983 Feb;153(2):1063-5. doi: 10.1128/jb.153.2.1063-1065.1983.
5
A pSC101-derived plasmid which shows no sequence homology to other commonly used cloning vectors.一种源自pSC101的质粒，与其他常用克隆载体无序列同源性。
Gene. 1984 Nov;31(1-3):165-71. doi: 10.1016/0378-1119(84)90207-5.
6
Quantal behavior of a diffusible factor which initiates septum formation at potential division sites in Escherichia coli.一种可扩散因子的量子化行为，该因子在大肠杆菌潜在分裂位点启动隔膜形成。
J Bacteriol. 1974 May;118(2):407-13. doi: 10.1128/jb.118.2.407-413.1974.
7
Identification and sequence of gene dicB: translation of the division inhibitor from an in-phase internal start.基因dicB的鉴定与序列：来自同相位内部起始的分裂抑制剂的翻译
Nucleic Acids Res. 1988 Jul 25;16(14A):6327-38. doi: 10.1093/nar/16.14.6327.
8
The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library.完整大肠杆菌染色体的物理图谱：一种用于大型基因组文库快速分析和分类的新策略的应用
Cell. 1987 Jul 31;50(3):495-508. doi: 10.1016/0092-8674(87)90503-4.
9
Direct cloning of specific genomic DNA sequences in plasmid libraries following fragment enrichment.片段富集后在质粒文库中直接克隆特定基因组DNA序列
Nucleic Acids Res. 1985 Nov 11;13(21):7569-78. doi: 10.1093/nar/13.21.7569.
10
Minicell-forming mutants of Escherichia coli: production of minicells and anucleate rods.大肠杆菌的微细胞形成突变体：微细胞和无核杆状菌的产生。
J Bacteriol. 1988 Jul;170(7):3094-101. doi: 10.1128/jb.170.7.3094-3101.1988.

大肠杆菌的小细胞形成突变体：通过使minC基因产物失活来抑制DicB和MinD依赖性的分裂抑制

Minicell-forming mutants of Escherichia coli: suppression of both DicB- and MinD-dependent division inhibition by inactivation of the minC gene product.

作者信息

Labie C, Bouché F, Bouché J P

机构信息

Centre de Recherches de Biochimie et de Génétique cellulaires du Centre National de la Recherche Scientifique, Toulouse, France.

出版信息

J Bacteriol. 1990 Oct;172(10):5852-5. doi: 10.1128/jb.172.10.5852-5855.1990.

DOI:10.1128/jb.172.10.5852-5855.1990
PMID:2211516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC526903/
Abstract

We have determined the nucleotide sequence of the minB operon of 10 min mutants of Escherichia coli, characterized by impaired inhibition of polar divisions. These mutants were either sensitive or resistant to the division inhibitor DicB. All the mutations were found to lie in minC or minD, confirming the requirement of both gene products in the process of inhibition of polar sites. Mutations conferring resistance to inhibitor DicB were found exclusively in minC. In agreement with de Boer et al. (P. A. J. de Boer, R. E. Crossley, and L. I. Rothfield, Proc. Natl. Acad. Sci. USA 87:1129-1133, 1990), these results provide evidence that, in addition to promoting division inhibition with MinD, protein MinC acts in concert with DicB to inhibit division by a second, MinD-independent process.

摘要

我们已经确定了10个大肠杆菌min突变体的minB操纵子的核苷酸序列，这些突变体的特征是对极性分裂的抑制受损。这些突变体对分裂抑制剂DicB要么敏感要么耐药。所有突变均位于minC或minD中，证实了这两种基因产物在抑制极性位点过程中的必要性。赋予对抑制剂DicB耐药性的突变仅在minC中发现。与德布尔等人（P.A.J.德布尔、R.E.克罗斯利和L.I.罗斯菲尔德，《美国国家科学院院刊》87:1129-1133，1990年）的研究结果一致，这些结果表明，除了与MinD一起促进分裂抑制外，MinC蛋白还与DicB协同作用，通过另一种不依赖MinD的过程抑制分裂。