Department of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons/New York Presbyterian Hospital, New York, New York, USA.
Ann Thorac Surg. 2011 Dec;92(6):2085-9. doi: 10.1016/j.athoracsur.2011.07.058.
Bradyarrhythmia requiring pacemaker placement is a relatively common complication after surgical ablation for atrial fibrillation (AF). We report our experience with surgical ablation procedures using various energy modalities and lesion sets in an attempt to identify the risk factors associated with postoperative pacemaker requirement.
Intraoperative data were collected prospectively, and preoperative and postoperative data were collected retrospectively. Energy modality and lesion sets used were dependent on availability on the date of the procedure and surgeon preference.
From October 1999 to October 2009, 701 patients underwent surgical ablation for AF at our institution. Forty-five patients (7.6%) required early postoperative pacemaker placement. There were no significant differences in baseline characteristics or associated procedures between patients who required pacemaker placement and those who did not. Ninety-day mortality was greater in patients requiring pacemaker placement (15.6% versus 6.6%; p = 0.025). In multivariable analysis, a pacemaker requirement was more likely with the use of microwave energy (odds ratio [OR] 2.87; confidence interval [CI], 1.41 to 5.84; p = 0.004) and a right atrial lesion set (OR, 2.82; CI, 1.07 to 7.45; p = 0.036).
In conclusion, over our 10-year experience with surgical AF ablations, the incidence of pacemaker requirement was much lower than that reported in series of classic "cut and sew" Maze procedures, even among patients undergoing full biatrial ablations. Although biatrial ablation is currently our favored approach to patients with long-standing or persistent AF, right atrial lesion sets increase the risk of this complication and should be used judiciously.
心脏外科消融术治疗心房颤动(房颤)后,发生需要起搏器植入的缓慢性心律失常是一种较为常见的并发症。我们报告了使用各种能量模式和消融策略的心脏外科消融术经验,旨在确定与术后需要起搏器相关的危险因素。
术中数据前瞻性收集,术前和术后数据回顾性收集。能量模式和消融策略的使用取决于手术当天的可用性和术者的偏好。
1999 年 10 月至 2009 年 10 月,我院共有 701 例患者因房颤行心脏外科消融术。45 例(7.6%)患者术后早期需要起搏器植入。需要起搏器植入的患者和不需要起搏器植入的患者在基线特征或相关手术方面无显著差异。需要起搏器植入的患者 90 天死亡率更高(15.6%比 6.6%;p = 0.025)。多变量分析显示,使用微波能量(比值比 [OR] 2.87;95%置信区间 [CI] 1.41 至 5.84;p = 0.004)和右心房消融策略(OR 2.82;CI 1.07 至 7.45;p = 0.036)更可能需要起搏器植入。
总之,在我们长达 10 年的心脏外科房颤消融术经验中,起搏器植入的发生率远低于经典“切割和缝合”迷宫手术系列报告的发生率,甚至在接受双侧心房消融的患者中也是如此。虽然双侧心房消融术目前是我们治疗长程或持续性房颤患者的首选方法,但右心房消融策略会增加这种并发症的风险,应谨慎使用。