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[口服抗凝剂在心房颤动中的风险与获益]

[Risk and benefit of oral anticoagulants in atrial fibrillation].

作者信息

Zotova I V, Zateĭshchikov D A

出版信息

Kardiologiia. 2011;51(10):81-91.

PMID:22117686
Abstract

Thromboembolism is the main cause of death and disability of patients with atrial fibrillation. Indirect anticoagulants are effective means of primary and secondary prevention of thromboembolic complications. However in a number of patients risk associated with therapy with indirect anticoagulants might exceed potential benefit. The principle problem requiring solution in a patient with atrial fibrillation is individual comparative assessment of risk of development of thromboembolic and hemorrhagic complications. Modern stratification scales which allow solving this problem are considered in this review.

摘要

血栓栓塞是房颤患者死亡和致残的主要原因。间接抗凝剂是预防血栓栓塞并发症一级和二级预防的有效手段。然而,在一些患者中,间接抗凝剂治疗相关的风险可能超过潜在益处。房颤患者需要解决的主要问题是对血栓栓塞和出血并发症发生风险进行个体比较评估。本综述讨论了有助于解决这一问题的现代分层量表。

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