Centro di Studio del Cavallo Sportivo, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.
Virus Res. 2012 Feb;163(2):656-9. doi: 10.1016/j.virusres.2011.11.011. Epub 2011 Nov 22.
Equine infectious anaemia virus (EIAV) is classified within the Retroviridae and, like other lentivirus, has the propensity for considerable antigenic variation. An extensive phylogenetic analysis in Bayesian fashion, with significant amounts of new EIAV gag sequence information, revealed a strong geographic compartmentalization clearly related to the phylogeographic history of modern horses, pointing out that New World EIAV strains form a distinct group with a potentially common origin. This evidence suggests that a single founder event may have occurred during the reintroduction of horses to the Americas by European colonists in the 15th century, a possibility that raises many interesting scenarios with implications for all evolutionary and ecological studies.
马传染性贫血病毒（EIAV）属于逆转录病毒科，与其他慢病毒一样，具有很强的抗原变异性。贝叶斯式的广泛系统发育分析，结合大量新的 EIAV gag 序列信息，揭示了一种强烈的地理分区，与现代马的系统地理历史密切相关，表明新世界 EIAV 毒株形成一个独特的群体，可能具有共同的起源。这一证据表明，15 世纪欧洲殖民者将马重新引入美洲时，可能发生了一次单一的创始事件，这一可能性为所有进化和生态研究带来了许多有趣的情景。
