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Binding and internalization of 125I-LDL in normal and mutant human fibroblasts. A quantitative autoradiographic study.

作者信息

Carpentier J L, Gorden P, Goldstein J L, Anderson R G, Brown M S, Orci L

出版信息

Exp Cell Res. 1979 Jun;121(1):135-42. doi: 10.1016/0014-4827(79)90453-1.

DOI:10.1016/0014-4827(79)90453-1
PMID:221225
Abstract
摘要

相似文献

1
Binding and internalization of 125I-LDL in normal and mutant human fibroblasts. A quantitative autoradiographic study.125I-低密度脂蛋白在正常及突变型人成纤维细胞中的结合与内化：一项定量放射自显影研究
Exp Cell Res. 1979 Jun;121(1):135-42. doi: 10.1016/0014-4827(79)90453-1.
2
Binding, internalization, and degradation of low density lipoprotein by normal human fibroblasts and by fibroblasts from a case of homozygous familial hypercholesterolemia.正常人成纤维细胞以及一名纯合子家族性高胆固醇血症患者的成纤维细胞对低密度脂蛋白的结合、内化和降解
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3
The LDL pathway in human fibroblasts: a receptor-mediated mechanism for the regulation of cholesterol metabolism.
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Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans.
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5
Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote.正常人成纤维细胞质膜上低密度脂蛋白受体的定位及其在家族性高胆固醇血症纯合子细胞中的缺失。
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Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein.对一种人类成纤维细胞突变株的分析，该突变株在受体结合型低密度脂蛋白的内化过程中存在缺陷。
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[Cholesterol transport by low-density lipoproteins and the problem of arteriosclerosis].[低密度脂蛋白的胆固醇转运与动脉硬化问题]
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Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.培养的人成纤维细胞对低密度脂蛋白的结合与降解。正常受试者与纯合子家族性高胆固醇血症患者细胞的比较。
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The LDL receptor and HMG-CoA reductase--two membrane molecules that regulate cholesterol homeostasis.
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Colloidal gold--low density lipoprotein conjugates as membrane receptor probes.胶体金-低密度脂蛋白复合物作为膜受体探针
Proc Natl Acad Sci U S A. 1981 Jan;78(1):368-71. doi: 10.1073/pnas.78.1.368.

引用本文的文献

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Analysis of receptor clustering on cell surfaces by imaging fluorescent particles.通过对荧光颗粒成像分析细胞表面的受体聚集情况。
Biophys J. 1994 Sep;67(3):1280-90. doi: 10.1016/S0006-3495(94)80600-9.
2
Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study.125I-胰高血糖素在离体大鼠肝细胞中的结合、内化及溶酶体关联。一项定量电子显微镜放射自显影研究。
J Clin Invest. 1980 Nov;66(5):1081-93. doi: 10.1172/JCI109937.
3
Surface redistribution of 125I-insulin in cultured human lymphocytes.
125I标记胰岛素在培养的人淋巴细胞中的表面再分布
J Cell Biol. 1981 Oct;91(1):17-25. doi: 10.1083/jcb.91.1.17.
4
Internalization of polypeptide hormones: mechanism, intracellular localization and significance.多肽激素的内化：机制、细胞内定位及意义
Diabetologia. 1980 Apr;18(4):263-74. doi: 10.1007/BF00251003.
5
Visualization of the binding, endocytosis, and transcytosis of low-density lipoprotein in the arterial endothelium in situ.低密度脂蛋白在动脉内皮中原位结合、内吞及转胞吞作用的可视化。
J Cell Biol. 1983 Jun;96(6):1677-89. doi: 10.1083/jcb.96.6.1677.
6
Endocytosis of the membrane immunoglobulins of mouse spleen B-cells: a quantitative study of its rate, amount and sensitivity to physiological, physical and cross-linking agents.小鼠脾脏B细胞膜免疫球蛋白的内吞作用：对其速率、数量以及对生理、物理和交联剂敏感性的定量研究
EMBO J. 1984 Oct;3(10):2235-42. doi: 10.1002/j.1460-2075.1984.tb02121.x.
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125I-thrombin binds to clustered receptors on noncoated regions of mouse embryo cell surfaces.125I-凝血酶与小鼠胚胎细胞表面无包被区域的聚集受体结合。
J Cell Biol. 1982 Dec;95(3):697-703. doi: 10.1083/jcb.95.3.697.
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Interactions of low density lipoprotein receptors with coated pits on human fibroblasts: estimate of the forward rate constant and comparison with the diffusion limit.低密度脂蛋白受体与人成纤维细胞上有被小窝的相互作用：正向速率常数的估计及与扩散极限的比较。
Proc Natl Acad Sci U S A. 1981 Sep;78(9):5695-8. doi: 10.1073/pnas.78.9.5695.
9
Inefficient internalization of receptor-bound low density lipoprotein in human carcinoma A-431 cells.人癌细胞A-431中受体结合型低密度脂蛋白的内化效率低下。
J Cell Biol. 1981 Feb;88(2):441-52. doi: 10.1083/jcb.88.2.441.
10
Binding, internalization, and lysosomal association of 125I-human growth hormone in cultured human lymphocytes: a quantitative morphological and biochemical study.125I-人生长激素在培养的人淋巴细胞中的结合、内化及溶酶体结合：一项定量形态学与生物化学研究
J Cell Biol. 1980 Nov;87(2 Pt 1):360-9. doi: 10.1083/jcb.87.2.360.