Vargo Lyn, Seri Istvan
National Association of Neonatal Nurses, Glenview, Illinois, USA.
Adv Neonatal Care. 2011 Aug;11(4):272-8. doi: 10.1097/ANC.0b013e318229263c.
The Management of Hypotension in the Very-Low-Birth-Weight Infant: Guideline for Practice, developed by Lyn Vargo, PhD, RN, NNP-BC, and Istvan Seri, MD, PhD, in 2011 under the auspices of the National Association of Neonatal Nurse Practitioners, focuses on the challenging topic of clinical management of systemic hypotension in the very low-birth-weight (VLBW) infant during the first 3 days of postnatal life. The recommendations and rationale in the excerpt below from the complete online publication are based on the best evidence available through both neonatal research and consultation of experts on the subject. They suggest a conservative, evidence-based treatment approach for the management of hypotension in the VLBW infant during the first 3 days of postnatal life that is logical, safe, and physiologically sound. The insufficient fund of knowledge on transitional cardiovascular physiology in general and pathophysiology in particular makes establishment of strict guidelines on the treatment of hypotension in VLBW neonates impossible. What becomes clear when presenting the evidence is how much more we need to know. Readers are strongly encouraged to refer to the complete text of the guideline, which has been endorsed by the American Academy of Pediatrics, for further understanding of this complex topic. The guideline is available free of charge at www.nann.org (click on Guidelines in the Education section).
实践指南，由林恩·瓦尔戈博士、注册护士、新生儿护士执业认证专家（NNP - BC）以及伊斯特万·塞里医学博士、哲学博士于2011年在美国新生儿护士执业者协会的支持下制定，聚焦于出生后前3天极低出生体重（VLBW）儿系统性低血压临床管理这一具有挑战性的主题。以下摘录自完整在线出版物中的建议和基本原理基于新生儿研究以及该主题专家咨询所获得的最佳证据。它们提出了一种保守的、基于证据的治疗方法，用于出生后前3天VLBW儿低血压的管理，该方法合理、安全且符合生理原理。总体而言，关于过渡性心血管生理学，尤其是病理生理学的知识储备不足，使得制定关于VLBW新生儿低血压治疗的严格指南变得不可能。在展示证据时变得清晰的是我们还有多少需要了解的。强烈鼓励读者参考已得到美国儿科学会认可的该指南全文，以进一步理解这个复杂的主题。该指南可在www.nann.org免费获取（点击教育板块中的指南）。
