Bhattacharjee D, Shetty T K, Sundaram K
Experientia. 1979 May 15;35(5):630-1. doi: 10.1007/BF01960364.
Enumeration of different types of spermatogonia, following a single i.p. administration of different doses of ethyl methanesulfonate in mice, showed a survival of A1-A4 and in spermatogonia is markedly reduced due to cell killing while the remaining types of spermatogonia were affected marginally. The cell killing effect was dose-dependent, and replenishment of these cells was observed by the end of one cycle of the seminiferous epithelium comprising of 8.5 days.
在给小鼠单次腹腔注射不同剂量的甲磺酸乙酯后，对不同类型精原细胞的计数显示，A1 - A4型精原细胞以及其他精原细胞的存活率因细胞杀伤而显著降低，而其余类型的精原细胞仅受到轻微影响。细胞杀伤效应呈剂量依赖性，并且在由8.5天组成的一个生精上皮周期结束时观察到了这些细胞的补充。
