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自发性高血压大鼠的血液和组织锌水平

Blood and tissue zinc levels in spontaneously hypertensive rats.

作者信息

Henrotte J G, Santarromana M, Franck G, Bourdon R

机构信息

CNRS, Faculty of Pharmacy, University of Paris V, France.

出版信息

J Am Coll Nutr. 1990 Aug;9(4):340-3. doi: 10.1080/07315724.1990.10720390.

DOI:10.1080/07315724.1990.10720390
PMID:2212392
Abstract

Zinc (Zn) determinations were performed on blood plasma and red cells, liver, heart, adrenals, and spleen of spontaneously hypertensive (SHR) and control normotensive (WKY) male rats, 20 weeks of age. SHR revealed higher red cell (p = 2 x 10(-5)) and heart (p = 0.007) Zn levels than WKY rats. The water content of organs was the same in the two strains. When compared with published data, these results suggest an association between high cell Zn levels and hypertension, the meaning of which is briefly discussed.

摘要

对20周龄的自发性高血压(SHR)雄性大鼠和对照正常血压(WKY)雄性大鼠的血浆、红细胞、肝脏、心脏、肾上腺及脾脏进行了锌(Zn)含量测定。结果显示,SHR大鼠的红细胞锌含量(p = 2×10⁻⁵)和心脏锌含量(p = 0.007)高于WKY大鼠。两种品系大鼠各器官的含水量相同。与已发表的数据相比,这些结果提示细胞内高锌水平与高血压之间存在关联,并对其意义进行了简要讨论。

相似文献

1
Blood and tissue zinc levels in spontaneously hypertensive rats.自发性高血压大鼠的血液和组织锌水平
J Am Coll Nutr. 1990 Aug;9(4):340-3. doi: 10.1080/07315724.1990.10720390.
2
High cardiac zinc levels in spontaneously hypertensive rats.自发性高血压大鼠心脏锌含量高。
J Hypertens. 1992 Jun;10(6):553-9. doi: 10.1097/00004872-199206000-00008.
3
Tissue and blood magnesium levels in spontaneously hypertensive rats, at rest and in stressful conditions.
Magnes Res. 1991 Jun;4(2):91-6.
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Some enzyme characteristics of spontaneously hypertensive rats myocardium.自发性高血压大鼠心肌的一些酶学特性
Jpn Circ J. 1990 Jun;54(6):688-94. doi: 10.1253/jcj.54.688.
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Anterior pituitary proopiomelanocortin expression is decreased in hypertensive rat strains.在高血压大鼠品系中,垂体前叶阿黑皮素原的表达降低。
Endocrinology. 1994 Jan;134(1):196-205. doi: 10.1210/endo.134.1.8275934.
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The adrenal synthesis and tissue content of dopamine increase when the blood pressure rises in spontaneously hypertensive rats.
J Hypertens Suppl. 1984 Dec;2(3):S127-9.
7
Enhanced DNA synthesis in heart and kidney of newborn spontaneously hypertensive rats.
Hypertension. 1986 Jun;8(6):520-5. doi: 10.1161/01.hyp.8.6.520.
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A defective beta-hydroxylation of dopamine may precede the full development of hypertension in spontaneously hypertensive rats.在自发性高血压大鼠中,多巴胺β-羟化缺陷可能先于高血压的完全发展出现。
Can J Cardiol. 1989 Sep;5(6):327-31.
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Altered carnitine metabolism in spontaneously hypertensive rats.自发性高血压大鼠中肉碱代谢的改变。
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Heart and red blood cell antioxidant status and plasma lipid levels in the spontaneously hypertensive and normotensive Wistar-Kyoto rat.自发性高血压和正常血压的Wistar-Kyoto大鼠的心脏和红细胞抗氧化状态及血浆脂质水平
Can J Physiol Pharmacol. 1996 Mar;74(3):290-7.

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