Henrotte J G, Santarromana M, Franck G, Bourdon R
CNRS, Faculty of Pharmacy, University of Paris V, France.
J Am Coll Nutr. 1990 Aug;9(4):340-3. doi: 10.1080/07315724.1990.10720390.
Zinc (Zn) determinations were performed on blood plasma and red cells, liver, heart, adrenals, and spleen of spontaneously hypertensive (SHR) and control normotensive (WKY) male rats, 20 weeks of age. SHR revealed higher red cell (p = 2 x 10(-5)) and heart (p = 0.007) Zn levels than WKY rats. The water content of organs was the same in the two strains. When compared with published data, these results suggest an association between high cell Zn levels and hypertension, the meaning of which is briefly discussed.
对20周龄的自发性高血压(SHR)雄性大鼠和对照正常血压(WKY)雄性大鼠的血浆、红细胞、肝脏、心脏、肾上腺及脾脏进行了锌(Zn)含量测定。结果显示,SHR大鼠的红细胞锌含量(p = 2×10⁻⁵)和心脏锌含量(p = 0.007)高于WKY大鼠。两种品系大鼠各器官的含水量相同。与已发表的数据相比,这些结果提示细胞内高锌水平与高血压之间存在关联,并对其意义进行了简要讨论。