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精神分裂症中的停止任务后效应:行为控制调整与重复启动

Stop task after-effects in schizophrenia: behavioral control adjustments and repetition priming.

作者信息

Enticott Peter G, Upton Daniel J, Bradshaw John L, Bellgrove Mark A, Ogloff James R P

机构信息

School of Psychology and Psychiatry, Monash University, Clayton, Victoria, Australia.

出版信息

Neurocase. 2012;18(5):405-14. doi: 10.1080/13554794.2011.627339. Epub 2011 Nov 29.

DOI:10.1080/13554794.2011.627339
PMID:22124369
Abstract

Stop task after-effects are behavioral consequences of response inhibition (i.e., slowed response time), and may index both behavioral control adjustments and repetition priming. Patients with schizophrenia and healthy controls completed a stop task, and responses to the go signal were analyzed according to characteristics of the immediately preceding trial. Schizophrenia was associated with reduced slowing following unsuccessful response inhibition, however there was no evidence of impairments in repetition priming. These results support neurocognitive models of schizophrenia that suggest an absence or reduction of behavioral adjustments (perhaps reflecting impaired error detection), but are inconsistent with current retrieval-based repetition priming accounts.

摘要

停止任务后效应是反应抑制的行为后果(即反应时间减慢),可能同时反映行为控制调整和重复启动。精神分裂症患者和健康对照者完成了一项停止任务,并根据紧接在前的试验特征分析对启动信号的反应。精神分裂症与反应抑制未成功后的减速减少有关,然而没有证据表明重复启动存在损伤。这些结果支持精神分裂症的神经认知模型,该模型表明行为调整缺失或减少(可能反映错误检测受损),但与当前基于检索的重复启动理论不一致。

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