Jiménez Jessica A, Greenberg Barry H, Mills Paul J
Department of Psychiatry, Behavioral Medicine Program, University of California, San Diego 9500 Gilman Drive, La Jolla, California 92093-0804.
Drug Discov Today Dis Models. 2011 Winter;8(4):161-166. doi: 10.1016/j.ddmod.2011.02.006.
Heart failure (HF) patients have a high prevalence of disturbed sleep. Optimal pharmacological management of HF includes the use of angiotensin converting enzyme inhibitors and β-blockers, which have been associated with decreased severity of central sleep apnea, which is likely secondary to improvements in cardiac performance. There is also evidence, however, indicating that other pharmacological treatments for HF might adversely affect sleep. This brief review introduces the topic of disturbed sleep in HF and examines the extent to which its standard pharmacological management impacts sleep quality.
心力衰竭（HF）患者睡眠障碍的患病率很高。HF的最佳药物治疗包括使用血管紧张素转换酶抑制剂和β受体阻滞剂，这些药物与中枢性睡眠呼吸暂停严重程度降低有关，这可能继发于心脏功能的改善。然而，也有证据表明，HF的其他药物治疗可能会对睡眠产生不利影响。这篇简短的综述介绍了HF患者睡眠障碍这一主题，并探讨了其标准药物治疗对睡眠质量的影响程度。
