Ostrup Esben, Hyttel Poul, Ostrup Olga
Section of Biomaterials, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, Norway.
Reprod Fertil Dev. 2011;23(8):964-75. doi: 10.1071/RD11140.
Communication during early pregnancy is essential for successful reproduction. In this review we address the beginning of the communication between mother and developing embryo; including morphological and transcriptional changes in the endometrium as well as epigenetic regulation mechanisms directing the placentation. An increasing knowledge of the embryo-maternal communication might not only help to improve the fertility of our farm animals but also our understanding of human health and reproduction.
妊娠早期的交流对于成功繁殖至关重要。在本综述中，我们探讨了母亲与发育中的胚胎之间交流的起始；包括子宫内膜的形态和转录变化以及指导胎盘形成的表观遗传调控机制。对胚胎 - 母体交流的了解不断增加，这不仅可能有助于提高我们农场动物的繁殖力，还能增进我们对人类健康和生殖的理解。
