Smith T J, Edelman I S
Fed Proc. 1979 Jul;38(8):2150-3.
The hypothesis that augmentation of Na+ transport activity mediates a significant fraction of thyroid thermogenesis is supported by studies on a wide range of target tissues. Recent criticisms based on theoretical and experimental considerations do not appear to negate the validity of this concept. A basic difficulty that remains to be resolved, however, is the development of techniques for assessing the contribution of the Na+ transport pathway to energy turnover in the intact animal.
关于钠转运活性增强介导了相当一部分甲状腺产热的假说，得到了对多种靶组织研究的支持。基于理论和实验考量的近期批评似乎并未否定这一概念的有效性。然而，一个有待解决的基本难题是开发评估钠转运途径对完整动物能量代谢贡献的技术。
