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孕期大鼠组织中的(钠 - 钾)-ATP酶活性

(Na+-K+)-ATPase activities in rat tissues during pregnancy.

作者信息

Zamora F, Arola L

机构信息

Department of Chemical Engineering and Biochemistry, University of Barcelona, Tarragona, Spain.

出版信息

Biol Res Pregnancy Perinatol. 1987;8(2 2D Half):89-92.

PMID:2827797
Abstract

(Na+-K+)-ATPase activities of liver, hind leg skeletal muscle, brain, perirenal white adipose tissue, interscapular brown adipose tissue and blood as well as placenta, fetal liver and fetal blood were determined in virgin rats and pregnant rats on days 12, 19 and 21 of gestation in order to evaluate its relative contribution either to metabolite transport processes or/and to thermogenesis during pregnancy. No changes were found in (Na+-K+)-ATPase activity in liver, blood and white adipose tissue in pregnant rats versus controls. (Na+-K+)-ATPase activity from muscle, brain and interscapular brown adipose tissue decreased during pregnancy and placenta showed an increase of (Na+-K+)-ATPase on day 21 of gestation in respect to day 12. No significant changes were observed either in fetal liver or fetal blood.

摘要

为了评估(钠钾)-ATP酶在代谢物转运过程或/和孕期产热中的相对作用,我们测定了未孕大鼠以及孕期第12、19和21天的孕鼠肝脏、后肢骨骼肌、脑、肾周白色脂肪组织、肩胛间棕色脂肪组织和血液,以及胎盘、胎儿肝脏和胎儿血液中的(钠钾)-ATP酶活性。与对照组相比,孕鼠肝脏、血液和白色脂肪组织中的(钠钾)-ATP酶活性未发生变化。孕期肌肉、脑和肩胛间棕色脂肪组织中的(钠钾)-ATP酶活性降低,胎盘在妊娠第21天的(钠钾)-ATP酶活性相对于第12天有所增加。胎儿肝脏和胎儿血液中均未观察到显著变化。

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