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[缩窄性心包炎的外科治疗]

[Surgical treatment of constrictive pericarditis].

作者信息

Tominaga R, Asou T, Nakano E, Masuda M, Kinoshita K, Kawachi Y, Tanaka J, Tokunaga K

机构信息

Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1990 Jul;38(7):1163-7.

PMID:2212778
Abstract

Since 1957, 30 patients with constrictive pericarditis have been treated surgically in Kyushu University Hospital. The surgical approaches were the left anterolateral thoracotomy in 17 patients (group I); the median sternotomy without cardiopulmonary bypass (CPB) in 6 patients (group II); and the median sternotomy with CPB in 7 patients (group III). The hospital mortality was 3.3 percent. The mean postoperative follow-up period was 11.7 years (longest 30 years). The actuarial survival rate at 5 years postoperatively was 88% in total cases (100% in group I, 82% in group II and 52% in group III), 88% at 10 years, 75% at 15 years and 67% at 20 years. Several patients in group III, who underwent complete pericardiectomy using CPB showed severe congestive heart failure and arrhythmia postoperatively. The comparative study between an poor result group (patients who died within 10 years post-operatively) and a good result group (patients who survived more than 10 years postoperatively revealed that preoperative hepatomegaly, atrial fibrillation and the interval between the onset of symptoms and the pericardiectomy influenced the survival rate significantly. These results suggested that pericardiectomy using CPB was a safe method for removing the calcified pericardium in the patient with severe constrictive pericarditis. However, a careful long term follow-up was necessary for the patient with severe myocardial damage even though the complete pericardiectomy was performed.

摘要

自1957年以来,九州大学医院对30例缩窄性心包炎患者进行了手术治疗。手术方式为:17例患者采用左前外侧开胸术(第一组);6例患者采用非体外循环(CPB)的正中胸骨切开术(第二组);7例患者采用CPB的正中胸骨切开术(第三组)。医院死亡率为3.3%。术后平均随访期为11.7年(最长30年)。所有病例术后5年的精算生存率为88%(第一组为100%,第二组为82%,第三组为52%),10年时为88%,15年时为75%,20年时为67%。第三组中几例采用CPB进行完全心包切除术的患者术后出现严重充血性心力衰竭和心律失常。对预后不良组(术后10年内死亡的患者)和预后良好组(术后存活超过10年的患者)进行的对比研究表明,术前肝肿大、心房颤动以及症状出现至心包切除术的间隔时间对生存率有显著影响。这些结果表明,对于重度缩窄性心包炎患者,采用CPB的心包切除术是一种安全的去除钙化心包的方法。然而,即使进行了完全心包切除术,对于有严重心肌损伤的患者仍需要进行仔细的长期随访。

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