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心包剥脱术治疗心包缩窄

Pericardiectomy for pericardial constriction.

作者信息

Trotter M C, Chung K C, Ochsner J L, McFadden P M

机构信息

Department of Surgery, Ochsner Clinic, New Orleans, Louisiana, 70121, USA.

出版信息

Am Surg. 1996 Apr;62(4):304-7.

PMID:8600853
Abstract

Constrictive pericarditis is a pathologic condition that may lead to significant morbidity. Definitive management of constrictive pericarditis requires pericardiectomy. A retrospective review of pericardiectomy for constrictive pericarditis at the Ochsner Clinic was undertaken. Twenty-one patients (17 male, four female) underwent pericardiectomy for constrictive pericarditis between January 1969 and June 1994. Ages ranged from 15 to 66 years (mean 41.5 years). Pedal edema, dyspnea, fatigue, and chest pain were the most common symptoms. Fifteen patients had important comorbidities. Preoperative New York Heart Association (NYHA) class was I (2), II (8), III (6), IV (5). Mean preoperative catheterization data, available in 17 patients (81%), demonstrated elevated intracardiac pressures (right atrial 17.4 mm Hg, right ventricular end-diastolic 22.4 mm Hg, pulmonary artery 26.2 mm Hg, pulmonary capillary wedge 20.2 mm Hg, left ventricular end-diastolic 20.1 mm Hg). A total pericardiectomy was performed in nine patients (sternotomy 8, thoracotomy 1). Pericardiectomy limited anteriorly to the phrenic nerves was performed in 11 patients (sternotomy 9, thoracotomy 2). One partial pericardiectomy was performed through a sternotomy. Cardiopulmonary bypass was used in six patients (29%). Mean hospital stay was 12 days (preoperative 4.2, postoperative 7.67). All patients achieved NYHA Class I postoperatively. Sixteen patients were discharged in sinus rhythm. No early mortality (<30 days), or major postoperative complications were observed. Pericardiectomy for pericardial constriction can be performed safely low morbidity and mortality and can favorably impact the natural history of this debilitating condition.

摘要

缩窄性心包炎是一种可能导致严重发病的病理状况。缩窄性心包炎的确切治疗需要心包切除术。对奥施纳诊所进行的缩窄性心包炎心包切除术进行了回顾性研究。1969年1月至1994年6月期间,21例患者(17例男性,4例女性)因缩窄性心包炎接受了心包切除术。年龄范围为15至66岁(平均41.5岁)。足部水肿、呼吸困难、疲劳和胸痛是最常见的症状。15例患者有重要的合并症。术前纽约心脏协会(NYHA)分级为I级(2例)、II级(8例)、III级(6例)、IV级(5例)。17例患者(81%)有可用的术前导管检查数据,显示心内压力升高(右心房17.4 mmHg,右心室舒张末期22.4 mmHg,肺动脉26.2 mmHg,肺毛细血管楔压20.2 mmHg,左心室舒张末期20.1 mmHg)。9例患者进行了全心包切除术(胸骨正中切开术8例,胸廓切开术1例)。11例患者进行了心包切除术,前方限于膈神经(胸骨正中切开术9例,胸廓切开术2例)。1例部分心包切除术通过胸骨正中切开术进行。6例患者(29%)使用了体外循环。平均住院时间为12天(术前4.2天,术后7.67天)。所有患者术后均达到NYHA I级。16例患者出院时为窦性心律。未观察到早期死亡(<30天)或重大术后并发症。心包缩窄的心包切除术可以安全地进行,发病率和死亡率低,并且可以对这种使人衰弱的疾病的自然病程产生有利影响。

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