Faghihi Reza, Mehdizadeh Simin, Sina Sedigheh, Alizadeh Fatemeh N, Zeinali Banafsheh, Kamyab Gholam Reza, Aghevlian Sadaf, Khorramdel Hossein, Namazi Imen, Heirani Mandana, Moshkriz Meisam, Mahani Hojjat, Sharifzadeh Mohsen
Radiation Research Center, School of Mechanical Engineering, Shiraz University, Mollasadra Street, Shiraz, Iran.
Radiat Prot Dosimetry. 2012 Jun;150(1):55-9. doi: 10.1093/rpd/ncr373. Epub 2011 Nov 28.
Radiographic imaging has a significant role in the timely diagnosis of the diseases of neonates in intensive care units. The estimation of the dose received by the infants undergoing radiographic examination is of great importance, due to greater more radiosensitivity and longer life expectancy of the neonates and premature babies. In this study, the values of entrance skin dose (ESD), dose area products (DAPs), energy imparted (EI), whole-body dose, effective dose and risk of childhood cancer were estimated using three methods including direct method [using thermoluminescence dosimetry (TLD) chips], indirect method (using tube output) and Monte Carlo (MC) method (using MCNP4C code). In the first step, the ESD of the neonates was directly measured using TLD-100 chips. Fifty neonates, mostly premature, with different weights and gestational ages in five hospitals mostly suffering from respiratory distress syndrome and pneumonia were involved in this study. In the second step, the values of ESD to neonates were indirectly obtained from the tube output in different imaging techniques. The imaging room, incubator, neonates and other components were then simulated in order to obtain the ESD values using the MCNP4C code. Finally, the values of ESD assessed by the three methods were used for calculation of DAP, EI, whole-body dose, effective dose and risk of childhood cancer. The results indicate that the mean ESD per radiograph estimated by the direct, indirect and MC methods are 56.6±4.1, 50.1±3.1 and 54.5±3.3 μGy, respectively. The mean risk of childhood cancer estimated in this study varied between 4.21×10(-7) and 2.72×10(-6).
放射成像在重症监护病房新生儿疾病的及时诊断中具有重要作用。由于新生儿和早产儿的放射敏感性更高且预期寿命更长,对接受放射检查的婴儿所接受剂量的估计非常重要。在本研究中,使用三种方法估计了皮肤入口剂量(ESD)、剂量面积乘积(DAP)、授予能量(EI)、全身剂量、有效剂量和儿童患癌风险,这三种方法包括直接法[使用热释光剂量测定(TLD)芯片]、间接法(使用管输出)和蒙特卡罗(MC)法(使用MCNP4C代码)。第一步,使用TLD - 100芯片直接测量新生儿的ESD。本研究纳入了五家医院的50名新生儿,大多数为早产儿,体重和胎龄各不相同,主要患有呼吸窘迫综合征和肺炎。第二步,通过不同成像技术中的管输出间接获得新生儿的ESD值。然后对成像室、保温箱、新生儿及其他组件进行模拟,以便使用MCNP4C代码获得ESD值。最后,将三种方法评估的ESD值用于计算DAP、EI、全身剂量、有效剂量和儿童患癌风险。结果表明,直接法、间接法和MC法估计的每张X线照片的平均ESD分别为56.6±4.1、50.1±3.1和54.5±3.3 μGy。本研究估计的儿童患癌平均风险在4.21×10⁻⁷至2.72×10⁻⁶之间。