Halachmi Shlomit, Lapidoth Moshe
Laser Unit, Department of Dermatology, Rabin Medical Center, Petach Tikva, Israel.
J Cosmet Laser Ther. 2012 Feb;14(1):2-6. doi: 10.3109/14764172.2011.634421.
Laser hair removal at lower fluences, delivered under certain conditions, may retain the efficacy of high-fluence lasers while improving tolerability. We performed a pilot study comparing the efficacy, safety and tolerability of laser hair removal using traditional settings compared to lower fluences, delivered from a larger handpiece and under vacuum.
Fourteen healthy participants underwent 5 axillary hair removal treatments with an 800 nm diode laser at 1-month intervals, with follow-up 1 and 3 months after the 5th treatment. In all patients, one side was treated with standard parameters using a 9×9 mm chilled tip and gel, while the contralateral side was treated using a 22×35 mm vacuum-assisted handpiece at fluences up to 12 J/cm(2). Follow-up assessments were performed after each treatment and at each follow-up visit, and included photography and questionnaires.
Eleven participants completed the study and follow-up. All experienced significant hair removal in all treated areas. At the 3-month follow-up visit, the high-fluence and low-fluence treated axillae demonstrated comparable hair reduction. Participants found the lower fluence treatments to be more tolerable. No adverse events were reported.
Lower fluence diode laser, delivered under conditions of vacuum and using larger spot sizes, can provide significant hair reduction.
在特定条件下以较低能量密度进行激光脱毛，可能在提高耐受性的同时保持高能量密度激光的疗效。我们进行了一项初步研究，比较了使用传统参数设置与通过较大手持件在真空条件下以较低能量密度进行激光脱毛的疗效、安全性和耐受性。
14名健康参与者使用800纳米二极管激光进行5次腋窝脱毛治疗，间隔1个月，在第5次治疗后1个月和3个月进行随访。所有患者一侧使用9×9毫米冷却头和凝胶按照标准参数治疗，而对侧使用22×35毫米真空辅助手持件，能量密度高达12 J/cm²进行治疗。每次治疗后及每次随访时进行随访评估，包括拍照和问卷调查。
11名参与者完成了研究和随访。所有治疗区域均有显著脱毛效果。在3个月的随访中，高能量密度和低能量密度治疗的腋窝毛发减少情况相当。参与者发现低能量密度治疗的耐受性更好。未报告不良事件。
在真空条件下使用较大光斑尺寸的低能量密度二极管激光可显著减少毛发。
