Department of Pediatric Endocrinology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
Eur J Clin Invest. 2012 Jun;42(6):623-30. doi: 10.1111/j.1365-2362.2011.02627.x. Epub 2011 Nov 30.
To establish the association between neck circumference and cardiometabolic risk factors and to determine the utility of the neck circumference as a parameter in predicting children at cardiometabolic risk.
Five - hundred and eighty-one children (461: overweight/obese, 120: normal body mass index) aged between 5 and 18 years were enrolled. Neck circumference, waist circumference, blood pressure and fasting plasma glucose, insulin, total cholesterol, triglyceride and high-density lipoprotein (HDL) cholesterol were recorded, and the homeostasis model assessment for insulin resistance score was calculated.
Neck circumference was negatively correlated with HDL cholesterol and positively correlated with all other parameters, with the exception of fasting plasma glucose in pubertal boys and girls and total cholesterol in pubertal girls. Linear regression analysis by designating neck circumference as a dependent variable revealed that insulin and TG levels in prepubertal boys and blood pressure and TG levels in pubertal boys were positively correlated with neck circumference. We found that diastolic blood pressure and insulin were positively correlated, while HDL levels were negatively correlated with neck circumference in prepubertal girls. Systolic blood pressure and insulin were positively correlated with neck circumference in pubertal girls. The cut-off value for neck circumference, as an indicator for metabolic syndrome (MS), was calculated as 36 cm in boys and 35 cm in girls.
Neck circumference measurement was shown to be associated with cardiometabolic risk factors in children. We suggest the use of neck circumference as a novel, simple, practical and reliable anthropometric index in predicting children at risk for cardiometabolic diseases.
本研究旨在探讨颈围与心血管代谢危险因素的相关性，并确定颈围作为预测儿童心血管代谢风险的参数的有效性。
本研究共纳入 581 名年龄在 5 至 18 岁之间的儿童（461 名超重/肥胖，120 名正常体重指数）。记录颈围、腰围、血压、空腹血糖、胰岛素、总胆固醇、甘油三酯和高密度脂蛋白胆固醇（HDL-C）水平，并计算胰岛素抵抗的稳态模型评估指数。
颈围与 HDL-C 呈负相关，与其他所有参数呈正相关，但青春期男、女的空腹血糖和青春期女的总胆固醇除外。以颈围为因变量的线性回归分析显示，青春期前男童的胰岛素和甘油三酯水平以及青春期男童的血压和甘油三酯水平与颈围呈正相关。我们发现，青春期前女童的舒张压和胰岛素与颈围呈正相关，而 HDL-C 水平与颈围呈负相关。青春期女童的收缩压和胰岛素与颈围呈正相关。颈围作为代谢综合征（MS）指标的截断值计算为男孩 36cm，女孩 35cm。
颈围测量与儿童心血管代谢危险因素相关。我们建议将颈围作为一种新的、简单、实用和可靠的人体测量指标，用于预测儿童患心血管代谢疾病的风险。
