中心动脉血压指数及其对心血管结局的影响。
Indices of central aortic blood pressure and their impact on cardiovascular outcomes.
机构信息
Department of Internal Medicine, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Blvd, Oklahoma City, OK 73104, USA.
出版信息
J Cardiovasc Med (Hagerstown). 2012 Jan;13(1):38-45. doi: 10.2459/JCM.0b013e32834ead20.
Elevated peripheral (brachial) blood pressure (PBP) is related to hard cardiovascular outcomes and remains the main target for antihypertensive therapy. However, central aortic blood pressure (CABP) can be measured noninvasively and could potentially prove to be a more important marker of cardiovascular diseases in future. Several studies have shown association of CABP with cardiovascular mortality, coronary artery disease, left-ventricular hypertrophy and atherosclerosis. Furthermore, the impact of various classes of antihypertensive agents on CABP is different from their impact on PBP. We review the significance of CABP in cardiovascular outcomes and the differential impact of antihypertensive therapy on CABP.
外周（肱）血压升高与心血管硬终点相关，仍然是降压治疗的主要目标。然而，主动脉根部血压可以无创测量，将来可能成为心血管疾病更重要的标志物。多项研究表明，主动脉根部血压与心血管死亡率、冠状动脉疾病、左心室肥厚和动脉粥样硬化有关。此外，各种降压药物对主动脉根部血压的影响与对肱动脉血压的影响不同。我们回顾了主动脉根部血压在心血管结局中的意义以及降压治疗对主动脉根部血压的不同影响。
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