哮喘儿童暴露于对乙酰氨基酚后，其对乙酰氨基酚代谢酶和谷胱甘肽表达降低。
Decreased expression of acetaminophen-metabolizing enzymes and glutathione in asthmatic children after acetaminophen exposure.
出版信息
J Allergy Clin Immunol. 2012 Mar;129(3):867-9. doi: 10.1016/j.jaci.2011.10.021. Epub 2011 Nov 30.
Abstract
Children with moderate-to-severe asthma have decreased expression of acetaminophen metabolizing genes and glutathione that may account for the previously-reported risk of acetaminophen in this vulnerable population.
摘要
患有中重度哮喘的儿童体内具有较低表达水平的对乙酰氨基酚代谢基因和谷胱甘肽，这可能解释了此前报道的这一脆弱人群使用对乙酰氨基酚存在风险的原因。
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