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玻璃体内注射曲安奈德后疑似坏死性病毒性视网膜炎:病例报告

Presumed necrotizing viral retinitis after intravitreal triamcinolone injection: case report.

作者信息

Han Jeong Mo, Ahn Jeeyun, Park Kyu Hyung, Woo Se Joon

机构信息

Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Korean J Ophthalmol. 2011 Dec;25(6):451-4. doi: 10.3341/kjo.2011.25.6.451. Epub 2011 Nov 22.

Abstract

A 56-year-old man presented with anterior chamber inflammation, increased intraocular pressure, peripheral retinal infiltration, and generalized retinal arterial obstruction suggesting acute retinal necrosis five months after intravitreal triamcinolone acetonide injection (IVTA). He was treated with intravenous antiviral agents and aspirin. Shortly after treatment, retinal infiltrations were resolved, and partial recanalization of the obstructed vessel was observed. Viral retinitis may occur as an opportunistic infection following IVTA due to the local immune modulatory effect of the steroid; hence, close observation following IVTA is necessary.

摘要

一名56岁男性在玻璃体内注射曲安奈德(IVTA)五个月后,出现前房炎症、眼压升高、周边视网膜浸润和广泛性视网膜动脉阻塞,提示急性视网膜坏死。他接受了静脉抗病毒药物和阿司匹林治疗。治疗后不久,视网膜浸润消退,观察到阻塞血管部分再通。由于类固醇的局部免疫调节作用,病毒性视网膜炎可能作为IVTA后的机会性感染发生;因此,IVTA后密切观察是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0af/3223715/da79933fad44/kjo-25-451-g001.jpg

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本文引用的文献

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Am J Ophthalmol. 2010 Mar;149(3):433-40.e1. doi: 10.1016/j.ajo.2009.10.019.
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Acute retinal necrosis post intravitreal injection of triamcinolone acetonide.
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