Wikesjö U M, Hagen K, Nielsen D D
School of Dentistry, Loma Linda University, CA.
J Periodontol. 1990 Sep;61(9):559-63. doi: 10.1902/jop.1990.61.9.559.
This study evaluated whether periodontal repair following reconstructive surgery may be compromised by saliva contamination of the root surfaces during the surgical procedure. Circumferential periodontal defects, 5 to 6 mm in vertical dimension, were surgically created in the mandibular premolars in 9 beagle dogs and immediately treated. The denuded root surfaces in left and right jaw quadrants in 4 dogs were treated with either filter sterilized saliva or saline, while in the remaining 5 dogs the root surfaces were treated with unfiltered saliva or saline. The wounds were closed and allowed to heal for 4 weeks. The dogs were sacrificed and tissue blocks prepared for histometric analysis. Results showed no difference between teeth treated with filtered or unfiltered saliva and the saline treated controls. Connective tissue repair to the root surfaces exceeded 70% of the defect height in all experimental groups. Regeneration of cementum and alveolar bone was limited and did not exceed 30% of the defect height. The results indicate that contamination of the root surface by saliva during the surgical procedure does not necessarily compromise connective tissue repair to the root surface.
本研究评估了在手术过程中牙根表面被唾液污染是否会损害重建手术后的牙周修复。在9只比格犬的下颌前磨牙上手术制造垂直尺寸为5至6毫米的环形牙周缺损，并立即进行治疗。4只犬左右颌象限的裸露牙根表面用过滤除菌的唾液或生理盐水处理，而其余5只犬的牙根表面用未过滤的唾液或生理盐水处理。伤口缝合，使其愈合4周。处死犬只并制备组织块用于组织计量学分析。结果显示，用过滤或未过滤唾液处理的牙齿与用生理盐水处理的对照组之间没有差异。所有实验组中，牙根表面的结缔组织修复超过缺损高度的70%。牙骨质和牙槽骨的再生有限，不超过缺损高度的30%。结果表明，手术过程中牙根表面被唾液污染不一定会损害牙根表面的结缔组织修复。
