Botta Luca, Cannata Aldo, Fratto Pasquale, Bruschi Giuseppe, Trunfio Salvatore, Maneggia Carla, Martinelli Luigi
Department of Cardiac Surgery, Niguarda Cà Granda Hospital, Milano, Italy.
J Card Surg. 2012 Jan;27(1):24-8. doi: 10.1111/j.1540-8191.2011.01358.x. Epub 2011 Dec 5.
We reviewed our experience to assess potential advantages of minimally invasive surgery without aortic clamping over conventional median sternotomy and cardioplegic arrest during reoperative valve surgery.
From August 2008 to August 2010, 22 reoperative valve procedures were performed through a minimally invasive approach without aortic cross-clamping [no-clamp group (NCG)]. Postoperative results were compared to a matched population in terms of sex, age, and type of surgery, and operated through median sternotomy with aortic cross-clamping and cardioplegic arrest [clamp group (CG)].
We performed 17 mitral valve replacements (MVRs), one mitral valve repair, one MVR associated to a tricuspid plasty (TVP), and three isolated TVP in both groups. Cardiopulmonary bypass (CPB) time was 166 and 163 minutes in NCG and CG, respectively. Intra-aortic balloon pump was necessary in two (NCG) and three (CG) patients. Two patients died in both groups from multiorgan failure. Biochemical analysis showed no significant differences in perioperative lactate or creatine kinase-MB values.
Redo valve surgery with an unclamped aorta is feasible, effective, and at least as safe as surgery using cardioplegic arrest. There was, however, no difference in biochemical or clinical outcomes from conventional surgery using aortic clamping and cardioplegic techniques.
我们回顾了自身经验,以评估再次手术瓣膜置换术中,与传统正中开胸和心脏停搏相比,非体外循环下微创手术的潜在优势。
2008年8月至2010年8月期间,22例再次手术瓣膜置换术通过非体外循环下微创手术方式完成(非体外循环组[NCG])。将术后结果与匹配的人群进行比较,匹配人群在性别、年龄和手术类型方面与研究对象一致,其手术方式为正中开胸、体外循环下心脏停搏(体外循环组[CG])。
两组均进行了17例二尖瓣置换术(MVR)、1例二尖瓣修复术、1例二尖瓣置换联合三尖瓣成形术(TVP)以及3例单纯三尖瓣成形术。非体外循环组和体外循环组的体外循环(CPB)时间分别为166分钟和163分钟。非体外循环组有2例、体外循环组有3例患者需要使用主动脉内球囊反搏。两组均有2例患者死于多器官功能衰竭。生化分析显示围手术期乳酸或肌酸激酶同工酶-MB值无显著差异。
非体外循环下再次瓣膜置换手术是可行、有效的,并且至少与使用心脏停搏技术的手术一样安全。然而,与使用体外循环和心脏停搏技术的传统手术相比,生化指标和临床结果并无差异。