Department of Physics, University of Parma, Parma, Italy.
Annu Rev Plant Biol. 2012;63:49-72. doi: 10.1146/annurev-arplant-042811-105538. Epub 2011 Nov 15.
Photoreceptor flavoproteins of the LOV, BLUF, and cryptochrome families are ubiquitous among the three domains of life and are configured as UVA/blue-light systems not only in plants-their original arena-but also in prokaryotes and microscopic algae. Here, we review these proteins' structure and function, their biological roles, and their evolution and impact in the living world, and underline their growing application in biotechnologies. We present novel developments such as the interplay of light and redox stimuli, emerging enzymatic and biological functions, lessons on evolution from picoalgae, metagenomics analysis, and optogenetics applications.
视蛋白类光感受器家族的 LOV、BLUF 和隐色素家族在生命的三个领域中无处不在，并且不仅在其原始领域——植物中，而且在原核生物和微型藻类中，都被配置为 UVA/蓝光系统。在这里，我们回顾了这些蛋白质的结构和功能、它们的生物学作用以及它们在生命世界中的进化和影响，并强调了它们在生物技术中的应用日益增加。我们介绍了一些新的发展，例如光和氧化还原刺激的相互作用、新兴的酶和生物学功能、从微型藻类中获得的进化教训、宏基因组学分析和光遗传学应用。
