AIDS Prevention and Research Center, National Yang-Ming University, Taipei, Taiwan.
BMC Infect Dis. 2011 Dec 5;11:334. doi: 10.1186/1471-2334-11-334.
Men having sex with men (MSM) accounts for 33.6% of all reported cases of HIV-1 infection in Taiwan. The aim of this study was to investigate the epidemiology of HIV-1 infection among MSM in gay saunas in Taiwan.
Patrons of 5 gay saunas were recruited for a weekly volunteer counseling and testing program from 2001 to 2005. Questionnaires were collected for a risk factor analysis. HIV-1 subtypes were determined using DNA sequencing and phylogenetic analyses.
HIV-1 prevalence rates among MSM in gay saunas in 2001 through 2005 were 3.4%, 5.1%, 8.9%, 8.5%, and 8.3%, respectively. In total, 81 of 1, 093 (7.4%) MSM had HIV-1 infection. Fifty-two HIV-1 strains were genotyped, and all of them were subtype B. HIV-seropositive men were significantly younger than the seronegatives. Only 37.1% used condoms every time during sexual intercourse. A multivariate logistic regression analysis showed that the risk factors for HIV-1 were being uncircumcised (odds ratio (OR) = 2.19; 95% confidence interval (CI), 1.084.45); having sexual intercourse with at least 2 partners during each sauna visit (≥ 2 vs. ≤ 1, OR = 1.71; 95% CI, 1.022.89); and the role played during anal intercourse (versatile vs. an exclusively insertive role, OR = 2.76; 95% CI, 1.42~5.36).
Overall, 7.4% Taiwanese MSM participating in this study had HIV-1 subtype B infection. Uncircumcised, being versatile role during anal intercourse, and having sex with more than one person during each sauna visit were main risk factors for HIV-1 infection.
男性同性恋者占台湾所有报告的 HIV-1 感染病例的 33.6%。本研究旨在调查台湾男同性恋浴室中男同性恋者的 HIV-1 感染的流行病学情况。
从 2001 年至 2005 年，每周招募 5 家男同性恋浴室的顾客参加志愿者咨询和检测计划。收集问卷进行危险因素分析。使用 DNA 测序和系统进化分析确定 HIV-1 亚型。
2001 年至 2005 年，男同性恋浴室男同性恋者的 HIV-1 流行率分别为 3.4%、5.1%、8.9%、8.5%和 8.3%。共有 1093 名男同性恋者中 81 人（7.4%）感染了 HIV-1。对 52 株 HIV-1 株进行了基因分型，均为 B 亚型。HIV-1 血清阳性的男性明显比血清阴性的年轻。只有 37.1%的人每次性行为都使用安全套。多变量 logistic 回归分析表明，HIV-1 的危险因素是未割礼（比值比（OR）=2.19；95%置信区间（CI），1.084.45）；每次浴室访问与至少 2 名性伴侣发生性关系（≥2 与≤1，OR=1.71；95%CI，1.022.89）；以及肛交时的角色（变装与仅插入角色，OR=2.76；95%CI，1.42~5.36）。
总的来说，7.4%参加这项研究的台湾男同性恋者感染了 HIV-1 亚型 B。未割礼、在肛交中扮演变装角色以及每次浴室访问时与多人发生性关系是感染 HIV-1 的主要危险因素。
