氟-18-氟代脱氧葡萄糖正电子发射断层扫描-计算机断层扫描检查中甲状腺意外瘤：发生率、恶性风险及标准化摄取值比较。
Thyroid incidentalomas on fluorine-18-fluorodeoxyglucose positron emission tomography-computed tomography: incidence, malignancy risk, and comparison of standardized uptake values.
机构信息
Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore.
出版信息
Can Assoc Radiol J. 2012 Nov;63(4):289-93. doi: 10.1016/j.carj.2011.04.003. Epub 2011 Dec 3.
INTRODUCTION
To determine the incidence of fluorine-18-fluorodeoxyglucose (FDG) avid thyroid incidentalomas detected on positron emission tomography (PET) with integrated computed tomography (CT), and correlate the FDG-PET-CT findings to cytology.
METHODS
A total of 942 FDG-PET-CT reports were retrospectively reviewed. Patients with FDG-avid thyroid incidentalomas were further reviewed for correlative cytology.
RESULTS
The incidence of FDG-avid thyroid incidentalomas is 2.2%. Thyroid malignancies were identified in 3 of 6 patients who underwent cytologic correlation, with a positive predictive value of 50% (95% confidence interval, 14%-86%). The mean maximum standardized uptake values of benign and malignant FDG-avid thyroid incidentalomas were 5.6 and 6.6, respectively.
CONCLUSION
A FDG-avid thyroid incidentaloma may predict underlying malignancy. Cytologic assessment should be considered for FDG-avid thyroid incidentalomas.
简介
为了确定正电子发射断层扫描（PET）与计算机断层扫描（CT）结合检测到的氟-18-氟代脱氧葡萄糖（FDG）摄取甲状腺偶发瘤的发生率，并将 FDG-PET-CT 结果与细胞学进行相关性分析。
方法
回顾性分析了 942 份 FDG-PET-CT 报告。对 FDG 摄取甲状腺偶发瘤的患者进行了进一步的细胞学相关性研究。
结果
FDG 摄取甲状腺偶发瘤的发生率为 2.2%。在 6 例进行细胞学相关性检查的患者中，有 3 例发现了甲状腺恶性肿瘤，阳性预测值为 50%（95%置信区间，14%-86%）。良性和恶性 FDG 摄取甲状腺偶发瘤的最大标准化摄取值平均值分别为 5.6 和 6.6。
结论
FDG 摄取甲状腺偶发瘤可能预示着潜在的恶性肿瘤。对于 FDG 摄取甲状腺偶发瘤应考虑进行细胞学评估。
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